Practice
Hepatopulmonary syndrome
Samir Gupta and Michael J. Krowka
CMAJ February 26, 2018 190 (8) E223; DOI: https://doi.org/10.1503/cmaj.170253
Samir Gupta
Department of Medicine (Gupta), University of Toronto; Division of Respirology (Gupta), St. Michael’s Hospital; Keenan Research Centre for Biomedical Science (Gupta), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ont.; Pulmonary and Gastroenterology/Hepatology Division (Krowka), Mayo Clinic, Rochester, Minn.
MD MScMichael J. Krowka
Department of Medicine (Gupta), University of Toronto; Division of Respirology (Gupta), St. Michael’s Hospital; Keenan Research Centre for Biomedical Science (Gupta), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ont.; Pulmonary and Gastroenterology/Hepatology Division (Krowka), Mayo Clinic, Rochester, Minn.
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Hepatopulmonary syndrome
Samir Gupta, Michael J. Krowka
CMAJ Feb 2018, 190 (8) E223; DOI: 10.1503/cmaj.170253
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- Hepatopulmonary syndrome is defined by liver disease, intrapulmonary vascular dilatation and abnormal oxygenation
- Hepatopulmonary syndrome is not uncommon among patients with liver disease
- Hepatopulmonary syndrome should be considered in patients with liver disease and an unexplained oxygen saturation of less than 96%, or any of platypnea, orthodeoxia, clubbing or cyanosis
- Liver transplantation is the only known cure for the syndrome
- Hepatopulmonary syndrome and portopulmonary hypertension are not the same disease
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