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The human microbiome
Bryan Coburn and David S. Guttman
CMAJ August 11, 2015 187 (11) 825; DOI: https://doi.org/10.1503/cmaj.141072
Bryan Coburn
Cell and Systems Biology, School of Graduate Studies (Coburn, Guttman); Centre for the Analysis of Genome Evolution and Function (Guttman), University of Toronto, Toronto, Ont.
MD PhDDavid S. Guttman
Cell and Systems Biology, School of Graduate Studies (Coburn, Guttman); Centre for the Analysis of Genome Evolution and Function (Guttman), University of Toronto, Toronto, Ont.
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The human microbiome
Bryan Coburn, David S. Guttman
CMAJ Aug 2015, 187 (11) 825; DOI: 10.1503/cmaj.141072
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- The healthy microbiome varies substantially across individuals and groups
- The human microbiome is essential for healthy development, metabolism and immunity
- Pathologic perturbation of the microbiome is increasingly recognized as an important correlate of infectious and noninfectious diseases
- Host behaviours and external factors, such as diet, exercise and medications, can influence the human microbiome
- Therapeutic manipulation of the human microbiome using microbiome transplantation or probiotics is a promising treatment for a variety of diseases
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