Review
Autism spectrum disorder: advances in evidence-based practice
Evdokia Anagnostou, Lonnie Zwaigenbaum, Peter Szatmari, Eric Fombonne, Bridget A. Fernandez, Marc Woodbury-Smith, Jessica Brian, Susan Bryson, Isabel M. Smith, Irene Drmic, Janet A. Buchanan, Wendy Roberts and Stephen W. Scherer
CMAJ April 15, 2014 186 (7) 509-519; DOI: https://doi.org/10.1503/cmaj.121756
Evdokia Anagnostou
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
MDLonnie Zwaigenbaum
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
MDPeter Szatmari
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
MDEric Fombonne
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
MDBridget A. Fernandez
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
MDMarc Woodbury-Smith
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
MD PhDJessica Brian
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
PhDSusan Bryson
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
PhDIsabel M. Smith
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
PhDIrene Drmic
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
PhDJanet A. Buchanan
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
PhDWendy Roberts
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
MDStephen W. Scherer
Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
PhDArticle Information
vol. 186 no. 7 509-519
PubMed
History
- Published online April 14, 2014.
Article Versions
- Latest version (January 13, 2014 - 08:26).
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© 2014 Canadian Medical Association or its licensors
Author Information
- Evdokia Anagnostou, MD,
- Lonnie Zwaigenbaum, MD,
- Peter Szatmari, MD,
- Eric Fombonne, MD,
- Bridget A. Fernandez, MD,
- Marc Woodbury-Smith, MD PhD,
- Jessica Brian, PhD,
- Susan Bryson, PhD,
- Isabel M. Smith, PhD,
- Irene Drmic, PhD,
- Janet A. Buchanan, PhD,
- Wendy Roberts, MD,
- Stephen W. Scherer, PhD⇑
- Holland Bloorview Kids Rehabilitation Centre (Roberts), Bloorview Research Institute (Anagnostou, Brian), Molecular Genetics (Scherer), McLaughlin Centre, University of Toronto, Toronto, Ont.; Department of Pediatrics (Zwaigenbaum), University of Alberta, Edmonton, Alta.; Department of Psychiatry (Szatmari), Austism Research Unit (Drmic, Roberts), The Centre for Applied Genomics (Buchanan, Scherer), The Hospital for Sick Children, Toronto, Ont.; Department of Child and Adolescent Psychiatry (Szatmari), Centre for Addiction and Mental Health, Toronto, Ont; Department of Psychiatry (Fombonne), Montreal Children’s Hospital, Montréal, Que.; McGill University (Fombonne), Montréal, Que.; Disciplines of Genetics and Medicine (Fernandez), Memorial University of Newfoundland, St. John’s, NL; Psychiatry and Behavioural Neurosciences (Woodbury-Smith), Offord Centre for Child Studies (Drmic), McMaster University, Hamilton, Ont.; Pediatrics and Psychology (Bryson, Smith), Dalhousie University, Halifax, NS; Autism Research Centre (Bryson, Smith), IWK Health Centre, Halifax, NS.
- Correspondence to: Stephen Scherer, stephen.scherer{at}sickkids.ca Evdokia Anagnostou, eanagnostou{at}hollandbloorview.ca
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Autism spectrum disorder: advances in evidence-based practice
Evdokia Anagnostou, Lonnie Zwaigenbaum, Peter Szatmari, Eric Fombonne, Bridget A. Fernandez, Marc Woodbury-Smith, Jessica Brian, Susan Bryson, Isabel M. Smith, Irene Drmic, Janet A. Buchanan, Wendy Roberts, Stephen W. Scherer
CMAJ Apr 2014, 186 (7) 509-519; DOI: 10.1503/cmaj.121756
Autism spectrum disorder: advances in evidence-based practice
Evdokia Anagnostou, Lonnie Zwaigenbaum, Peter Szatmari, Eric Fombonne, Bridget A. Fernandez, Marc Woodbury-Smith, Jessica Brian, Susan Bryson, Isabel M. Smith, Irene Drmic, Janet A. Buchanan, Wendy Roberts, Stephen W. Scherer
CMAJ Apr 2014, 186 (7) 509-519; DOI: 10.1503/cmaj.121756
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