Skip to main content

Main menu

  • Home
  • COVID-19
    • Articles & podcasts
    • Blog posts
    • Collection
    • News
  • Content
    • Current issue
    • Past issues
    • Early releases
    • Collections
    • Sections
    • Blog
    • Infographics & illustrations
    • Podcasts
  • Authors
    • Overview for authors
    • Submission guidelines
    • Submit a manuscript
    • Forms
    • Editorial process
    • Editorial policies
    • Peer review process
    • Publication fees
    • Reprint requests
  • CMA Members
    • Overview for members
    • Earn CPD Credits
    • Print copies of CMAJ
    • Career Ad Discount
  • Subscribers
    • General information
    • View prices
  • Alerts
    • Email alerts
    • RSS
  • JAMC
    • À propos
    • Numéro en cours
    • Archives
    • Sections
    • Abonnement
    • Alertes
    • Trousse média 2021
  • CMAJ JOURNALS
    • CMAJ Open
    • CJS
    • JAMC
    • JPN

User menu

Search

  • Advanced search
CMAJ
  • CMAJ JOURNALS
    • CMAJ Open
    • CJS
    • JAMC
    • JPN
CMAJ

Advanced Search

  • Home
  • COVID-19
    • Articles & podcasts
    • Blog posts
    • Collection
    • News
  • Content
    • Current issue
    • Past issues
    • Early releases
    • Collections
    • Sections
    • Blog
    • Infographics & illustrations
    • Podcasts
  • Authors
    • Overview for authors
    • Submission guidelines
    • Submit a manuscript
    • Forms
    • Editorial process
    • Editorial policies
    • Peer review process
    • Publication fees
    • Reprint requests
  • CMA Members
    • Overview for members
    • Earn CPD Credits
    • Print copies of CMAJ
    • Career Ad Discount
  • Subscribers
    • General information
    • View prices
  • Alerts
    • Email alerts
    • RSS
  • JAMC
    • À propos
    • Numéro en cours
    • Archives
    • Sections
    • Abonnement
    • Alertes
    • Trousse média 2021
  • Visit CMAJ on Facebook
  • Follow CMAJ on Twitter
  • Follow CMAJ on Pinterest
  • Follow CMAJ on Youtube
  • Follow CMAJ on Instagram
Highlights

Highlights

CMAJ October 18, 2011 183 (15) 1685;
  • Article
  • Responses
  • Metrics
  • PDF
Loading

Sudden cardiac arrest

Figure1
Image courtesy of © 2011 Thinkstock

The incidence of sudden cardiac arrest was higher in poorer neighbourhoods than in richer neighbourhoods in seven North American cities studied, although the association was less marked in Canada than in the US. Reinier and colleagues analyzed data from a population-based registry of sudden cardiac arrests occurring outside hospital and census data linked to patients’ places of residence. The authors suggest that efforts to reduce cardiovascular risk factors and to improve survival from sudden cardiac arrest be targeted to lower-income communities to reduce disparities in incidence. See Research, page 1705

The highest incidence of premature, sudden cardiac arrest occurs in populations with low socioeconomic status. Population-based efforts to reduce cardiovascular risk factors among lower-income communities may be the most effective strategy to combat the single most common cause of death in western societies. See Commentary, page 1692

NSAIDs may not be safe in pregnancy

Taking nonaspirin nonsteroidal anti-inflammatory drugs was associated with more than doubling of the risk of spontaneous abortion. Examining routine data from a provincial pregnancy registry and drug plan, Nakhai-Pour and colleagues conducted a case–control analysis comparing 4705 women who had had a spontaneous abortion with 10 times the number of women in the control group. These drugs should be used with caution during pregnancy, say the authors. See Research, page 1713

Serious causes of syncope

The San Francisco Syncope Rule should be applied only for patients in whom no cause of syncope is evident after initial evaluation in the emergency department. Saccilotto and colleagues reviewed and summarized 12 studies in this bivariate meta-analysis and found a pooled sensitivity of 87% and pooled specificity of 52% for detecting a serious outcome. Whether the accuracy of the rule could be improved by routinely including information from cardiac monitoring may be an avenue for further research, say the authors. See Research, page E1116

Figure2
Image courtesy of © 2011 Thinkstock

Educated clinical judgment based on evidence-based guidelines seems to be the best strategy for the management of patients presenting to emergency departments with syncope. See Commentary, page 1694

Prevalence of metabolic syndrome

Figure3
Image courtesy of © 2011 Thinkstock

One in five Canadian adults had metabolic syndrome in 2007–2009. This prevalence measure is based on data from the cross-sectional Canadian Health Measures Survey. Public health initiatives to improve dietary habits and physical activity are needed, say the authors. See Research, page E1127

C-CHANGE Initiative

Figure4
Image courtesy of © 2011 Thinkstock

With many guidelines available for risk management of cardiovascular disease, it can be difficult for physicians to determine which ones to use, which risk factors to address first and which treatment targets to follow. The C-CHANGE Initiative used a consensus model to harmonize and integrate more than 400 recommendations into a more manageable package of key recommendations. The authors stress that most patients at moderate and high risk of cardiovascular events will require a combination of modifications to health behaviours and pharmacologic interventions to meet treatment targets. See Guidelines, page E1135

Enteric fever

Vaccines licensed for the prevention of typhoid fever confer only partial protection against typhoid fever, while the oral formulation provides partial protection against one type of paratyphoid infection additionally. Beaulieu and Boggild stress that a history of immunization against typhoid does not preclude enteric fever as a diagnosis in returned travellers with fever. See Practice, page 1740

Pyoderma gangrenosum

In patients with rapidly progressive ulceration occurring after trauma, negative results on microbiological analysis should prompt consideration of pyoderma gangrenosum as a diagnosis. See Practice, page 1746

PreviousNext
Back to top

In this issue

Canadian Medical Association Journal: 183 (15)
CMAJ
Vol. 183, Issue 15
18 Oct 2011
  • Table of Contents
  • Index by author

Article tools

Print
Download PDF
Article Alerts
To sign up for email alerts or to access your current email alerts, enter your email address below:
Email Article

Thank you for your interest in spreading the word on CMAJ.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Highlights
(Your Name) has sent you a message from CMAJ
(Your Name) thought you would like to see the CMAJ web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Highlights
CMAJ Oct 2011, 183 (15) 1685;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
‍ Request Permissions
Share
Highlights
CMAJ Oct 2011, 183 (15) 1685;
Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Sudden cardiac arrest
    • NSAIDs may not be safe in pregnancy
    • Serious causes of syncope
    • Prevalence of metabolic syndrome
    • C-CHANGE Initiative
    • Enteric fever
    • Pyoderma gangrenosum
  • Responses
  • Metrics
  • PDF

Related Articles

  • Pyoderma gangrenosum associated with chronic polyarthritis
  • Socioeconomic status and incidence of sudden cardiac arrest
  • Use of nonaspirin nonsteroidal anti-inflammatory drugs during pregnancy and the risk of spontaneous abortion
  • Prediction and prevention of sudden cardiac arrest
  • Current issues with prediction rules for syncope
  • San Francisco Syncope Rule to predict short-term serious outcomes: a systematic review
  • Prevalence of metabolic syndrome in the Canadian adult population
  • Harmonization of guidelines for the prevention and treatment of cardiovascular disease: the C-CHANGE Initiative
  • Enteric fever in two vaccinated travellers to Latin America
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Highlights
  • Highlights
  • Highlights
Show more Highlights

Similar Articles

Content

  • Current issue
  • Past issues
  • Collections
  • Sections
  • Blog
  • Podcasts
  • Alerts
  • RSS
  • Early releases

Information for

  • Advertisers
  • Authors
  • Reviewers
  • CMA Members
  • Media
  • Reprint requests
  • Subscribers

About

  • General Information
  • Journal staff
  • Editorial Board
  • Governance Council
  • Journal Oversight
  • Careers
  • Contact
  • Copyright and Permissions

Copyright 2021, Joule Inc. or its licensors. All rights reserved. ISSN 1488-2329 (e) 0820-3946 (p)

All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association or its subsidiaries.

To receive any of the resources on this site in an accessible format, please contact us at cmajgroup@cmaj.ca.

Powered by HighWire