- © 2005 Canadian Medical Association or its licensors
Don Vinh's hypothesis is interesting. However, the toxins of Clostridium perfringens essentially result in severe necrotizing enteritis, sparing the large bowel, in contrast to the hypervirulent C. difficile, which causes severe colitis,1 with little involvement of the small bowel. Nevertheless, the mechanism postulated deserves further investigation.
Reference
- 1.↵