A 32-year-old heterosexual Japanese man presented with a 2-week history of painful
gangrene-like cheilitis (Figure 1A) and generalized asymptomatic pustular eruptions (Figure …

A single spirochete was identified using immunohistochemical staining (Figure 1B).
Laboratory workup revealed positive IgG and IgM treponemal antibodies and reactive rapid …

A 45-year-old divorced man who has just been released from prison, presented with a
week's history of pustular eruption on the face and a flu-like syndrome (fever, chills, and sore …

A 35-year-old Japanese man visited our hospital with a 2-year history of skin lesions
affecting his palms and soles. The palmar lesions comprised diffuse papillomatous …

A 37-year-old man with HIV infection (CD4+ cell count 706 cells/μL, viral load undetectable)
presented with a 3-month history of cough, pharyngitis, low-grade fevers and dark black …

Background Pustular syphilis is an extremely rare manifestation of secondary syphilis.
Failure to recognize the disease can have devastating consequences. Methods We present …

A22-year-old black woman was admitted to the hospital because of high fever, malaise, sore
throat, and a cutaneous eruption. One month prior to admission, she noticed a skin rash on …

Dear Sir, A 24-year-old unmarried man came to OPD to get himself screened 10 days after
he had an unprotected sexual exposure with a known female contact. He had a history of …

Figure 1. A 32-year-old man presented with a five-day history of nonpruritic, copper-colored
palmoplantar macules and papules (Panels A and B), several of which were crossed by …

Syphilis remains a public health problem worldwide. The disease is associated with
increased risk of acquisition or transmission of human immunodeficiency virus (HIV), and …