To respond to Alex Porzecanski's specific question, the patient that we described1 did indeed have a defective afferent pupillary response in the left eye, as would be expected with optic neuritis.
We can now provide an update on the patient's situation. He returned to the Hospital for Sick Children 4 months later with complete blindness in the left eye (the one with the defective afferent pupillary response). Repeat MRI showed multiple new lesions of the periventricular white matter. This MRI evidence of dissemination in time and space confirmed the diagnosis of multiple sclerosis.
Aleixo Muise Linda Hiraki Shaun Morris Department of Pediatrics Hospital for Sick Children Toronto, Ont.
Reference
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