Characteristics and outcomes of hospital admissions for COVID-19 and influenza in the Toronto area
…, HY Jung, M Fralick, SL Malecki, L Lapointe-Shaw… - Cmaj, 2021 - Can Med Assoc
BACKGROUND: Patient characteristics, clinical care, resource use and outcomes associated
with admission to hospital for coronavirus disease 2019 (COVID-19) in Canada are not …
with admission to hospital for coronavirus disease 2019 (COVID-19) in Canada are not …
[HTML][HTML] Understanding the use and perceived impact of a medical podcast: qualitative study
Background: Although podcasts are increasingly being produced for medical education,
their use and perceived impact in informal educational settings are understudied. Objective: …
their use and perceived impact in informal educational settings are understudied. Objective: …
[HTML][HTML] A genetic model for multimorbidity in young adults
Purpose Multimorbidity is increasing in younger adults but is understudied in this population.
We used 22q11.2 deletion syndrome (22q11.2DS) as a genetic model to investigate …
We used 22q11.2 deletion syndrome (22q11.2DS) as a genetic model to investigate …
[HTML][HTML] 22q11. 2 microdeletion and increased risk for type 2 diabetes
L Van, T Heung, SL Malecki, C Fenn, A Tyrer… - …, 2020 - thelancet.com
Background The 22q11.2 microdeletion is the pathogenic copy number variation (CNV)
associated with 22q11.2 deletion syndrome (22q11.2DS, formerly known as DiGeorge syndrome…
associated with 22q11.2 deletion syndrome (22q11.2DS, formerly known as DiGeorge syndrome…
Identifying clusters of coexisting conditions and outcomes among adults admitted to hospital with community-acquired pneumonia: a multicentre cohort study
Background: Little is known about patterns of coexisting conditions and their influence on
clinical care or outcomes in adults admitted to hospital for community-acquired pneumonia (…
clinical care or outcomes in adults admitted to hospital for community-acquired pneumonia (…
[HTML][HTML] Variations in long-term care home resident hospitalizations before and during the COVID-19 pandemic in Ontario
Objectives To examine how the COVID-19 pandemic affected the demographic and clinical
characteristics, in-hospital care, and outcomes of long-term care residents admitted to …
characteristics, in-hospital care, and outcomes of long-term care residents admitted to …
[HTML][HTML] Young adults with a 22q11. 2 microdeletion and the cost of aging with complexity in a population-based context
SL Malecki, T Heung, WP Wodchis, R Saskin… - Genetics in …, 2024 - Elsevier
Purpose Information about the impact on the adult health care system is limited for complex
rare pediatric diseases, despite their increasing collective prevalence that has paralleled …
rare pediatric diseases, despite their increasing collective prevalence that has paralleled …
Patient characteristics, clinical care, resource use, and outcomes associated with hospitalization for COVID-19 in the Toronto area
…, HY Jung, M Fralick, SL Malecki, L Lapointe-Shaw… - medRxiv, 2020 - medrxiv.org
Background Patient characteristics, clinical care, resource use, and outcomes associated
with hospitalization for coronavirus disease (COVID-19) in Canada are not well described. …
with hospitalization for coronavirus disease (COVID-19) in Canada are not well described. …
[HTML][HTML] Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2
…, D Vardar-Ulu, S L'Heureux, T Ashworth, MJ Malecki… - PloS one, 2009 - journals.plos.org
Background Notch receptors are normally cleaved during maturation by a furin-like protease
at an extracellular site termed S1, creating a heterodimer of non-covalently associated …
at an extracellular site termed S1, creating a heterodimer of non-covalently associated …
[HTML][HTML] Caractéristiques et issues des hospitalisations pour les cas de COVID-19 et d'influenza dans la région de Toronto
…, HY Jung, M Fralick, SL Malecki, L Lapointe-Shaw… - CMAJ, 2021 - Can Med Assoc
CONTEXTE: Les caractéristiques des patients, les soins cliniques, l’utilisation des ressources
et les issues cliniques des personnes atteintes de la maladie à coronavirus 2019 (COVID-…
et les issues cliniques des personnes atteintes de la maladie à coronavirus 2019 (COVID-…