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Production of cleft palate with dexamethasone and hypervitaminosis A in rat embryos

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Durch Verabreichung von Dexamethason und hohen Dosen Vitamin A bei graviden Wistar-Albinoratten wurden im Embryo experimentell Gaumenspalten erzeugt, nicht aber mit Cortisonazetat. Dexamethason und Vitamin-A-Hypervitaminose ergaben gleiche histologische Bilder.

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Acknowledgments. I wish to thank Dr. H.Boersma for help in the preparation of the manuscript.

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Nanda, R., van der Linden, F.P.G.M. & Jansen, H.W.B. Production of cleft palate with dexamethasone and hypervitaminosis A in rat embryos. Experientia 26, 1111–1112 (1970). https://doi.org/10.1007/BF02112705

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