Low-dose hydrocortisone in patients with cirrhosis and septic shock: a randomized controlled trial
Background Recent studies have reported a high prevalence of relative adrenal
insufficiency in patients with liver cirrhosis. However, the effect of corticosteroid replacement …
insufficiency in patients with liver cirrhosis. However, the effect of corticosteroid replacement …
[PDF][PDF] Adrenal insufficiency in patients with cirrhosis and septic shock: effect of treatment with hydrocortisone on survival
J Fernández, A Escorsell, M Zabalza, V Felipe… - …, 2006 - Wiley Online Library
Relative adrenal insufficiency is frequent in patients with severe sepsis and is associated
with hemodynamic instability, renal failure, and increased mortality. This study prospectively …
with hemodynamic instability, renal failure, and increased mortality. This study prospectively …
[PDF][PDF] Adrenal insufficiency in patients with cirrhosis, severe sepsis and septic shock
MH Tsai, YS Peng, YC Chen, NJ Liu, YP Ho… - …, 2006 - Wiley Online Library
Patients with cirrhosis are susceptible to bacterial infection, which can result in circulatory
dysfunction, renal failure, hepatic encephalopathy, and a decreased survival rate. Severe …
dysfunction, renal failure, hepatic encephalopathy, and a decreased survival rate. Severe …
Assessment of adrenocortical reserve in stable patients with cirrhosis
G Fede, L Spadaro, T Tomaselli, G Privitera, S Piro… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: Adrenal insufficiency (AI) is reported in critically ill patients with
cirrhosis and is associated with increased mortality. It is unclear if AI is an underlying …
cirrhosis and is associated with increased mortality. It is unclear if AI is an underlying …
[HTML][HTML] Update on adrenal insufficiency in patients with liver cirrhosis
A Trifan, S Chiriac, C Stanciu - World Journal of Gastroenterology …, 2013 - ncbi.nlm.nih.gov
Liver cirrhosis is a major cause of mortality worldwide, often with severe sepsis as the
terminal event. Over the last two decades, several studies have reported that in septic …
terminal event. Over the last two decades, several studies have reported that in septic …
Adrenal insufficiency in liver disease–what is the evidence?
Recently, treatment with corticosteroids in the setting of septic shock and adrenal
insufficiency has been shown to decrease mortality. In septic patients, a blunted response to …
insufficiency has been shown to decrease mortality. In septic patients, a blunted response to …
Critical illness-related corticosteroid insufficiency in patients with cirrhosis and variceal bleeding
CK Triantos, M Marzigie, G Fede, M Michalaki… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS: Relative adrenal insufficiency (AI) occurs in patients with cirrhosis
with sepsis, but not with variceal bleeding. We evaluated adrenal function in cirrhotic …
with sepsis, but not with variceal bleeding. We evaluated adrenal function in cirrhotic …
[PDF][PDF] Adrenocortical dysfunction in liver disease: a systematic review
G Fede, L Spadaro, T Tomaselli, G Privitera… - …, 2012 - Wiley Online Library
In patients with cirrhosis, adrenal insufficiency (AI) is reported during sepsis and septic
shock and is associated with increased mortality. Consequently, the term “hepato‐adrenal …
shock and is associated with increased mortality. Consequently, the term “hepato‐adrenal …
Including relative adrenal insufficiency in definition and classification of acute-on-chronic liver failure
Background & Aims Relative adrenal insufficiency (RAI) is defined by insufficient production
of cortisol relative to organ demand. RAI is observed frequently in hospitalized patients with …
of cortisol relative to organ demand. RAI is observed frequently in hospitalized patients with …
[PDF][PDF] Relative adrenal insufficiency in decompensated cirrhosis: relationship to short‐term risk of severe sepsis, hepatorenal syndrome, and death
J Acevedo, J Fernández, V Prado, A Silva… - …, 2013 - Wiley Online Library
The prevalence of relative adrenal insufficiency (RAI) in critically ill cirrhosis patients with
severe sepsis is over 60% and associated features include poor liver function, renal failure …
severe sepsis is over 60% and associated features include poor liver function, renal failure …
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