Re-rethinking the article by Thombs and colleagues
First, unacceptably high false-positive rates can result. To support this point, Thombs and
colleagues offered one reference that claimed there are 50% falsepositive rates, whereas …
colleagues offered one reference that claimed there are 50% falsepositive rates, whereas …
Technology-assisted risk of bias assessment in systematic reviews requires precise definitions of risk of bias
L Puljak - Journal of clinical epidemiology, 2018 - jclinepi.com
[1] Wallach JD, Gonsalves GS, Ross JS. Research, regulatory, and clinical decision-making:
the importance of scientific integrity. J Clin Epidemiol 2018; 93: 88e93.[2] National Institutes …
the importance of scientific integrity. J Clin Epidemiol 2018; 93: 88e93.[2] National Institutes …
A survey of experts to identify methods to detect problematic studies: Stage 1 of the INSPECT-SR Project
Abstract Background Randomised controlled trials (RCTs) inform healthcare decisions.
Unfortunately, some published RCTs contain false data, and some appear to have been …
Unfortunately, some published RCTs contain false data, and some appear to have been …
[HTML][HTML] Comparison of protocols and registry entries to published reports for systematic reviews
D Pieper, K Allers, T Mathes, F Hoffmann… - The Cochrane …, 2020 - ncbi.nlm.nih.gov
Background Systematic reviews of studies comparing the effects of interventions are
considered the most valid and reliable evidence to support people making decisions and …
considered the most valid and reliable evidence to support people making decisions and …
[HTML][HTML] Restoring the integrity of the clinical trial evidence base
Public confidence in the credibility of medical research is at a low ebb. 1 2 3 4 Many
completed clinical trials have never been published, and many published results are …
completed clinical trials have never been published, and many published results are …
Evaluating systematic reviews and meta-analyses
LA Bero - JL & Pol'y, 2006 - HeinOnline
Information overload in the medical field is not a new problem. In fact, it just gets worse as
more information of questionable validity accumulates. As much of this information appears …
more information of questionable validity accumulates. As much of this information appears …
Attack of zombie reviews? JBI Evidence Synthesis editors discuss the commentary “definition, harms, and prevention of redundant systematic reviews”
In the commentary, they discussed the problems associated with redundancy in systematic
reviews, while also acknowledging the need for research duplication (and the delicate …
reviews, while also acknowledging the need for research duplication (and the delicate …
[HTML][HTML] ROBIS: a new tool to assess risk of bias in systematic reviews was developed
P Whiting, J Savović, JPT Higgins, DM Caldwell… - Journal of clinical …, 2016 - Elsevier
Objective To develop ROBIS, a new tool for assessing the risk of bias in systematic reviews
(rather than in primary studies). Study Design and Setting We used four-stage approach to …
(rather than in primary studies). Study Design and Setting We used four-stage approach to …
[PDF][PDF] An amnesty for unpublished trials
I Roberts, JR Hoey - CMAJ, 1997 - Can Med Assoc
Reports of properly conducted randomized controlled trials are the foundation of effective
health care, yet many are never submitted for publication. 1, 2 This reduces the power of …
health care, yet many are never submitted for publication. 1, 2 This reduces the power of …
Discussion: Why “An estimate of the science-wise false discovery rate and application to the top medical literature” is false
JPA Ioannidis - Biostatistics, 2014 - academic.oup.com
Jager and Leek have tried to estimate a false-discovery rate (FDR) in abstracts of articles
published in five medical journals during 2000–2010. Their approach is flawed in sampling …
published in five medical journals during 2000–2010. Their approach is flawed in sampling …
