From the department of pharmacology, University of British Columbia, Vancouver Reprint
requests to: Dr. Thomas L. Perry, Department of pharmacology, Faculty of medicine …

Both genetics and epidemiology are scientific disci-plines with a theoretical basis that, in
genetics especially, has widespread applications for all living organisms. Both are also …

Hun TIN G TON'S chorea is an uncommon condition with which most practitioners will have
little acquaintance. Those who have cases in their practice will be frequently called on for …

The relative fertility of sons and daughters of patients with Huntington's chorea was found to
be a little under 0.5 if they had been told of their risk of transmitting the disease before they …

The finding of a genetically linked polymorphic DNA marker has made possible a predictive
test for Huntington's chorea. This DNA probe has so far been used only for research and has …

A long-term programme to reduce the incidence of Huntington's Chorea has been
established in South Wales, based on a study of all individuals known to be affected or at …

" Index Medicus" and 18 other publications have been consulted in an attempt to provide an
easily assimilated selection of the recently published and widely dispersed material relevant …

Huntington's chorea is one ofthe most serious genetic disorders of adult life.'It is far from
rare: around 3000 people in Britain are affected at any one time, while the number at high …

All health professionals within a defined geographical area who had any knowledge of, or
contact with, patients with Huntington's chorea or their relatives were contacted and …

Ninety-two patients suffering from Huntington's chorea (HC) and their spouses, and 91
subjects with an affected parent and their spouses, living in three counties of industrial South …