Heparin-induced thrombocytopenia

SD Jevtic, AM Morris, TE Warkentin, M Pai - CMAJ, 2021 - Can Med Assoc
Heparin-induced thrombocytopenia is an uncommon condition mediated by anti-PF4
platelet-activating antibodies that typically begins 5–14 days after heparin initiation. Overall …

Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation

TL Ortel - ASH Education Program Book, 2009 - ashpublications.org
Heparin-induced thrombocytopenia (HIT) is an immune-mediated disorder caused by the
development of antibodies to platelet factor 4 (PF4) and heparin. The thrombocytopenia is …

Heparin-induced thrombocytopenia

GM Lee, GM Arepally - Hematology 2013, the American Society …, 2013 - ashpublications.org
Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder caused by antibodies
that recognize complexes of platelet factor 4 (PF4) and heparin. HIT is frequently considered …

Heparin-induced thrombocytopenia: diagnosis and management

K Hassell - Thrombosis research, 2008 - Elsevier
Heparin-induced thrombocytopenia (HIT) is an immune reaction in response to platelet
factor 4-heparin complexes, which results in increased platelet activation and …

How I treat heparin-induced thrombocytopenia

A Cuker, DB Cines - Blood, The Journal of the American …, 2012 - ashpublications.org
Heparin-induced thrombocytopenia is a prothrombotic adverse drug effect induced by
platelet-activating antibodies against multimolecular complexes of platelet factor 4 and …

[HTML][HTML] Pathogenic Antibodies in Heparin-Induced Thrombocytopenia Specifically Target an Immunodominant Region on Platelet Factor 4

A Huynh, DM Arnold, JG Kelton, R Clare, M Ivanova… - Blood, 2019 - Elsevier
Introduction: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction that
occurs when heparin binds to platelet factor 4 (PF4) forming immunogenic complexes. Anti …

Heparin-induced thrombocytopenia

A Pishko, A Cuker - Transfusion Medicine and Hemostasis, 2019 - Elsevier
Heparin-induced thrombocytopenia is a prothrombotic iatrogenic disorder induced by
platelet-activating antibodies that target multimolecular complexes of platelet factor 4 and …

Heparin-induced thrombocytopenia

GM Arepally, TL Ortel - Annual review of medicine, 2010 - annualreviews.org
Heparin-induced thrombocytopenia (HIT) is an immune-mediated hypercoagulable disorder
caused by antibodies to platelet factor 4 (PF4) and heparin. HIT develops in temporal …

[PDF][PDF] Heparin induced thrombocytopenia.

Y Nazlı, N Çolak, S Çolak, Ö Çakır - Journal of Clinical & …, 2014 - cyberleninka.org
Heparin-induced thrombocytopenia (HIT) is a rare but serious prothrombotic adverse effect
of heparin treatment. It is induced by platelet-activating antibodies against complexes of …

[HTML][HTML] DiagnoSTic assays for heparin-induced thrombocytopenia

EE Gardiner, RK Andrews, A Cuker - British journal of haematology, 2014 - ncbi.nlm.nih.gov
Heparin-induced thrombocytopenia (HIT) is a sporadic and unpredictable disorder that
predisposes to thrombosis. The thrombocytopenia observed in HIT is manifest by the …