How Canada can better embed randomized trials into clinical care
S Murthy, RA Fowler, A Laupacis - CMAJ, 2020 - Can Med Assoc
CMAJ| AUGUST 10, 2020| VOLUME 192| ISSUE 32 E929 access to interprovincially shared
routinely collected clinical data (more rapid than the months to a year it currently takes to …
routinely collected clinical data (more rapid than the months to a year it currently takes to …
Integrating research into clinical practice: challenges and solutions for Canada
F Lamontagne, KM Rowan, G Guyatt - Cmaj, 2021 - Can Med Assoc
A common perception that research is a costly diversion from clinical care exacerbates this
problem and makes it difficult to persuade sites to participate in clinical studies. Furthermore …
problem and makes it difficult to persuade sites to participate in clinical studies. Furthermore …
Generating randomized trial evidence to optimize treatment in the COVID-19 pandemic
We believe that Canada needs to ensure the necessary infrastructure is in place to support
enrolment of patients with COVID-19 in treatment trials, making it simple for all clinicians to …
enrolment of patients with COVID-19 in treatment trials, making it simple for all clinicians to …
Improving evidence generation through point-of-care trials
C Propes, T Locke, R Hendricks-Sturrup - Health Affairs Forefront, 2022 - healthaffairs.org
We are witnessing an increasing demand for rapid, rigorous, and generalizable evidence to
inform health care systems' learning and address inefficiencies in the current clinical trials …
inform health care systems' learning and address inefficiencies in the current clinical trials …
[PDF][PDF] Australia needs a prioritised national research strategy for clinical trials in a pandemic: lessons learned from COVID‐19
The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), sparking a global pandemic, 1 has driven an imperative to quickly design and conduct …
2), sparking a global pandemic, 1 has driven an imperative to quickly design and conduct …
[PDF][PDF] The landscape of COVID-19 trials in Australia
AL Seidler, M Aberoumand, JG Williams… - Medical Journal of …, 2021 - mja.com.au
This perspective explores the landscape of COVID-19 trials recruiting in Australia using trial
registry data. We identified 56 trials addressing treatment and prevention of COVID-19, and …
registry data. We identified 56 trials addressing treatment and prevention of COVID-19, and …
Infrastructure challenges to doing health research “where populations with the most disease live” in Covid times—a response to Rai et al.(2021)
J MacLellan, J Turnbull, C Pope - BMC Medical Research Methodology, 2022 - Springer
Background The failure of randomised controlled trials to adequately reflect areas of highest
health need have been repeatedly highlighted. This has implications for the validity and …
health need have been repeatedly highlighted. This has implications for the validity and …
Democratising the design and delivery of large-scale randomised, controlled clinical trials in primary care: A personal view
CC Butler - European Journal of General Practice, 2024 - Taylor & Francis
Background Rapid identification of effective treatments for use in the community during a
pandemic is vital for the well-being of individuals and the sustainability of healthcare …
pandemic is vital for the well-being of individuals and the sustainability of healthcare …
Timely access to trial data in the context of a pandemic: the time is now
R Li, J Wood, A Baskaran, S Neumann, E Graham… - BMJ open, 2020 - bmjopen.bmj.com
Objective Clinical trial data sharing has the potential to accelerate scientific progress,
answer new lines of scientific inquiry, support reproducibility and prevent redundancy. Vivli …
answer new lines of scientific inquiry, support reproducibility and prevent redundancy. Vivli …
How COVID-19 has fundamentally changed clinical research in global health
JJH Park, R Mogg, GE Smith… - The Lancet Global …, 2021 - thelancet.com
COVID-19 has had negative repercussions on the entire global population. Despite there
being a common goal that should have unified resources and efforts, there have been an …
being a common goal that should have unified resources and efforts, there have been an …