A 52-year-old woman with a seven-year history of seropositive rheumatoid arthritis treated
with oral prednisolone (5 mg/d) and methotrexate (6 mg/wk) presented after two weeks of …

A 57 year old gentleman presented with multiple nodular swellings over dorsal aspects of
hands (Figure 1), forearms (Figure 2), posterior superior iliac spine and over back (Figure 2) …

Methotrexate (MTX)-induced accelerated nodulosis (MIAN) reportedly occurs in patients with
rheumatic arthritis receiving MTX therapy. However, it has also been reported in patients …

Rheumatoid nodulosis is characterized by multiple small subcutaneous granulomatous
nodules typically located on the elbows in approximately 20% of patients with rheumatoid …

SIR, Accelerated nodulosis (AN) is a well-known complication of methotrexate (MTX)
therapy in rheumatoid arthritis (RA) patients [1], characterized by the rapid appearance of …

Accelerated nodulosis (AN) is a potential complication of methotrexate (MTX) therapy for
rheumatoid arthritis (RA). We report on a 62-year old man affected by seropositive RA who …

DISCUSSION Many case reports and reviews have been published on MTX-induced
accelerated nodulosis. Most reported cases occurred in patients with RA and some in …

Methotrexate (MTX) nodulosis in patients with rheumatoid arthritis treated with MTX has
become a well recognized phenomenon. It has not been described in patients receiving …

DISCUSSION Rheumatoid nodules occur in approximately 25% of patients with RA. 1 Most
commonly, rheumatoid nodules occur in the subcutaneous tissue over the elbows in areas …

Accelerated nodulosis, the rapid progression/extension of preexisting nodules, is a
recognized complication of immunomodulatory therapy, occurring mostly in patients with …