Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo …

SA Halperin, B Smith, C Nolan, J Shay, J Kralovec - Cmaj, 2003 - Can Med Assoc
Background: Enhancement of immune function has been claimed as a benefit of some
natural health products, although few have been subjected to randomized clinical trials. We …

[HTML][HTML] Beneficial immunostimulatory effect of short-term Chlorella supplementation: enhancement of Natural Killercell activity and early inflammatory response …

JH Kwak, SH Baek, Y Woo, JK Han, BG Kim, OY Kim… - Nutrition journal, 2012 - Springer
Background In vitro and animal studies have demonstrated that Chlorella is a potent
biological response modifier on immunity. However, there were no direct evidences for the …

[HTML][HTML] Salivary secretory immunoglobulin A secretion increases after 4-weeks ingestion of chlorella-derived multicomponent supplement in humans: a randomized …

T Otsuki, K Shimizu, M Iemitsu, I Kono - Nutrition journal, 2011 - Springer
Background Chlorella, a unicellular green alga that grows in fresh water, contains high
levels of proteins, vitamins, minerals, and dietary fibers. Some studies have reported …

Stimulation of cytokine production in human peripheral blood mononuclear cells by an aqueous Chlorella extract

HS Ewart, O Bloch, GS Girouard, J Kralovec… - Planta …, 2007 - thieme-connect.com
CPE is an aqueous extract of the edible micro alga Chlorella pyrenoidosa, which has been
shown to have immunostimulatory effects in vivo. In the present study, CPE was evaluated …

[HTML][HTML] Effect of broccoli sprouts and live attenuated influenza virus on peripheral blood natural killer cells: a randomized, double-blind study

L Müller, M Meyer, RN Bauer, H Zhou, H Zhang… - PloS one, 2016 - journals.plos.org
Enhancing antiviral host defense responses through nutritional supplementation would be
an attractive strategy in the fight against influenza. Using inoculation with live attenuated …

Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A (H1N1) virus infection

ND Pugh, D Edwall, L Lindmark, KG Kousoulas… - Phytomedicine, 2015 - Elsevier
A growing body of research indicates that oral administration of bacteria (such as probiotics)
can exhibit a protective effect against influenza A (H1N1) viral infection in mice. In the …

[HTML][HTML] Effect of supplementation with Chlorella vulgaris on lipid profile in adults: A systematic review and dose-response meta-analysis of randomized controlled …

N Sherafati, MV Bideshki, M Behzadi, S Mobarak… - … Therapies in Medicine, 2022 - Elsevier
Objective To summarize available findings on the effect of Chlorella vulgaris
supplementation on lipid profile in adults. Design Systematic review and meta-analysis of …

Effect of Chlorella vulgaris on immune-enhancement and cytokine production in vivo and in vitro

HJ An, HK Rim, JH Lee, MJ Seo, JW Hong… - Food Science and …, 2008 - koreascience.kr
The object of this study was to investigate the immune-enhancing effects of Chlorella
vulgaris (CV) on a deteriorated immune function by a protein-energy malnutrition (PEM) diet …

Immunostimulatory Bioactivity of Algal Polysaccharides from Chlorella pyrenoidosa Activates Macrophages via Toll-Like Receptor 4

HY Hsu, N Jeyashoke, CH Yeh, YJ Song… - Journal of agricultural …, 2010 - ACS Publications
Much research suggests that a dietary supplement of Chlorella pyrenoidosa may be helpful
to human health, but the molecular mechanism involved remains unclear. The aim of this …

Short-term supplementation with active hexose correlated compound improves the antibody response to influenza B vaccine

BE Roman, E Beli, DM Duriancik, EM Gardner - Nutrition Research, 2013 - Elsevier
Administration of bioactive nutritional supplements near or at the time of immunization has
been a recent approach to stimulate human immune response to vaccination. Active hexose …