complete freedom to participate in and approve all aspects of industrysponsored clinical
trials, including any publication resulting from such a trial. We encourage all authors to abide …

This paper provides historical background to the contemporary interest in medical ethics in
the United States and examines conflicts of interest between the parties involved in medical …

The pharmaceutical industry has become the single largest direct source of funds for
medical research in Canada, the UK and the US. Conflicts of interest are inevitable because …

If you want to keep a secret, put it into your “Information for Authors”; no one ever reads that
stuff, goes a joke among medical journal editors. True, that section is dull and full of fussy …

Ever since the horrors of Nazi human experimentation were revealed following World War II,
the clinical research community has been continuously re-examining and strengthening …

Ethical reasons are presented for requiring 1) that a proposal for a clinical trial should be
accompanied by a thorough review of all previous trials that have examined the same and …

There have been recent, heightened concerns about the integrity and credibility of industry-
sponsored clinical research. While attributable to a variety of factors, the potential …

Barry Koehler misunderstands the nature and purpose of our proposed oversight
mechanisms. 1 It is actually less complicated and bureaucratic to standardize the principles …

In this paper several issues are examined that arise from con ducting randomized clinical
trials in a family practice setting. The distinctive research tradition in family practice involves …

All new medicinal products are extensively tested prior to marketing. Promising new drugs
are first tested on animals, then on healthy human volunteers.'Thereafter, they are tested on …