Epidemiology has published 1700 articles with “smoking” in their titles or abstracts, and only
4% of them considered how genetic variants affect smoking-related health outcomes.“After …

Tobacco use remains the leading cause of preventable death in the US, emphasizing the
need to understand which genes and environments are involved in the establishment of …

The NIEHS and its fellow NIH institutes and centers have joined forces to reveal still more
connections between genes, the environment, and human health. On 6 February 2006 …

As our understanding of genetics has improved, genome-wide association studies (GWAS)
have identified numerous variants associated with lifestyle behaviours and health outcomes …

Given our strong agreement with Gwinn et al.'s (1) position on the importance of integrating
studies of genetic and environmental contributors to health risk, we were intrigued by their …

The candidate genex environment (cGx E) interaction literature has proved controversial,
perhaps nowhere more so than in relation to the putative moderating effect of 5-HTTLPR …

It has been said by many that the public-policy-driven campaign to reduce smoking has
been the single most effective public health movement of the last 50 years (Issacs & …

If genetics research is ever to fulfill its promise of revolutionizing medicine, genotypes must
be linked to phenotypes—that is, individual genomic characteristics must be identified and …

Cigarette smoking is influenced both by genetic and environmental factors. Until this year, all
large-scale gene identification studies on smoking were conducted in populations of …

CMAJ• SEPTEMBER 23, 2008• 179 (7) 630 are the result of the interaction of multiple
genetic and environmental factors that remain to be identified. 12 Through their family …