Abstract Typus Degenerativus Amstelodamensis or Amsterdam dwarfism, a syndrome of
unknown etiology characterized by mental retardation, a distinctive face, characteristic …

Symptoms and signs are described of 5 patients whose clinical features correspond closely
to the syndrome described by de Lange in 1933 as “typhus degenerativus …

In 1933, Cornelia de Lange 1 of Amsterdam called attention to the first of a group of children
2-14 with a syndrome whose principal clinical findings include a typical facies with a small …

IN 1933, Cornelia de Lange of Amsterdam described a peculiar and distinctive combination
of congenital anomalies which she modestly named 'Typus degenerativus …

The four unrelated infants with identical and characteristic faces described here were seen
by a number of paediatricians at different times in different parts of England. All four were …

DID LANGE'S SYNDROME is named after Dr. Cornelia de Lange, the Dutch pllldiatrician
who in 1933 described the first two cases (de Lange, 1933). Her paper was entitled" On a …

IN 1933, de Lange in Amsterdam described two patients with a complex syndrome
associated with characteristic facies and cluster of various congenital anomalies. The …

In 1933l and 193P de Lange described a congenital syndrome characterized by mental and
physical retardation, hirsutism, microcephaly, and deformities of the face and extremities …

Three hundred ten individuals with a clinical diagnosis of de Lange syndrome were seen
and examined in conjunction with the parent support group. One hundred thirty‐four males …

CONGENITAL disorders associated with failure of physical and mental development are
common and their pathogenesis is seldom well understood. The finding of abnormal …