Bench research versus clinical trials: Where should Canadian grant dollars go?

PC Lee - CMAJ, 2000 - Can Med Assoc
As Dr. Sackett noted in his commentary, Canada is far behind the US, Japan and Europe in
biochemistry, biological sciences, preclinical studies and anatomy. 5 Rather than limiting …

Bench research versus clinical trials: Where should Canadian grant dollars go?

DL Sackett - CMAJ, 2000 - Can Med Assoc
trials (including Canadian ones) can't occur without bench research (especially Canadian).
But doesn't his assertion overlook about 35 000 surgical, educational and health care trials …

Canadian Clinical Trials Coordinating Centre

B Tholl - CMAJ, 2014 - Can Med Assoc
We are glad to hear that the World Health Organization (WHO) has conducted an
emergency meeting to establish new control centres to contain the spread of Ebola in West …

Clinical research in Canada: the dawn of a new era?

JL Rouleau - Clinical and Investigative Medicine, 2009 - utpjournals.press
In response to the growing gap between discovery and the optimal application of medical
advancements to health care delivery, countries the world over have developed large and …

American universities operate fewer industry trials

K Novak - Nature Medicine, 2003 - nature.com
If not finished, then academia's love affair with industry-sponsored trials in the United States
is certainly cooling. According to CenterWatch, the independent clinical trials monitor …

Clinical trials: the muddled Canadian landscape

A Silversides - 2009 - Can Med Assoc
This overview of the landscape of Canadian clinical trials, along with a historical primer
(page 23), is the first in a series of articles CMAJ will present this year on the state of clinical …

Bench to bedside and back again may be key to clinical breakthroughs

T Hampton - JAMA, 2017 - jamanetwork.com
Very few treatments tested in pre-clinical studies make their way into clinical trials—of 5000
compounds tested in animals, approximately 5 will show enough promise in human trials for …

[HTML][HTML] The perilous state of independent randomized clinical trials and related applied research in Canada

S Yusuf, J Cairns - CMaJ, 2012 - Can Med Assoc
• The Canadian Institutes of Health Research (CIHR), preferably with the creation of a new
agency or vice-presidential position for human applied research, should increase funding for …

[HTML][HTML] From bedside to bench and back again

R Collier - 2011 - Can Med Assoc
The space between the potential benefit of a medical research project and real improvement
in a clinical setting is sometimes closer to a gulf than a gap. If actual patients are to actually …

[CITATION][C] Chasing Medical Miracles: The Promise and Perils of Clinical Trials

NM Goldfarb - 2010