The antileukotrienes have now been extensively evaluated in clinical trials involving patients
with persistent asthma, as is comprehensively reviewed by Paolo Renzi elsewhere in this …

Use of antileukotrienes is not recommended as first-line monotherapy in patients with
asthma, except those who have aspirin intolerant asthma. Patients with concomitant allergic …

Antileukotriene agents may be reasonable and safe alternatives or adjuncts to inhaled
steroid therapy in chronic asthma, as they act at sites further down in the inflammatory …

Use of antileukotriene agents in asthma management Page 1 COMP THER. 2000;26(1):31–38
31 ORIGINALARTICLE SHELDON L. SPECTOR, MD University of California at Los Angeles …

While clinical data suggest that inhaled corticosteroids may offer greater improvements in
asthma control, the antileukotriene agents (ALAs) offer potential advantages in ease of …

Patients suffering from mild asthma are divided into intermittent or persistent classes based
on frequency of symptoms and reliever medication usage. Although these terms are used as …

Leukotrienes are derived from the cell membrane phospholipid arachidonic acid and are
members of a larger group of molecules known as eicosanoids. It is possible to inhibit the …

The antileukotriene drugs are the first new therapeutic agents approved for the treatment of
asthma in more than 20 years. The currently available compounds are orally active and …

Asthma management is an evolving process which has culminated in the publication of
numerous national and international guidelines for the treatment of the disease. Despite this …

The role of inflammation in asthma has been the main theme of various guidelines on its
treatment and the emphasis of the National Asthma Education Program (NAEP). There are …