About 7 years ago I conducted a follow-up study of nearly 100 patients who 10 years earlier
had been found to have mild to moderate essential hypertension. Those under 40 years of …

The haemodynamic effects of drugs affecting the neutral control of blood pressure in
humans can be considered from various standpoints. A long list could be produced of …

The hemodynamic mechanisms responsible for the increased blood pressure in the various
types of hypertension in animals and man have now been studied for almost 30 years. In the …

Fig. 1 due to high blood pressure to have been reduced by 52%, as indicated in the age
group of males from 45 to 64. Similarly, and even more impressive are current figures from …

612 AMERICAN HEART JOURNAL out that many drugs are praised in the absence of
controlled clinical observations. Thirty-three drugs, in all, were exhibited by them, including …

SINCE the average life expectancy of hypertensive patients is less than that of the general
population1 2 3 4 5 the question arises whether it is advisable to lower the blood pressure …

Clinical trials evaluating the effects of treatment with antihyp sive drugs on the prevention of
the complications of hypertensi been limited almost exclusively to patients with severe hyper …

Structural vascular changes, consisting mainly of smooth muscle cell hypertrophy of the
arterioles, have been found in various hypertensive animal models as well as in …

Previous studies have indicated the existance of haemodynamically important structural
vascular changes in patients and animals with hypertension. Possible pathophysiological …

While low calorie diets, moderate salt restriction, avoidance of mental or physical strain and
sedation continue to be preferred for mild cases of hyper tension, there are indications that …