A15-year-old girl presented with a two-day history of fever, confusion and rash. On
examination, she had hypotension, stiffness of the neck and a purpuric rash covering her …

A 6-month-old infant presented with a 2-day history of fever, irritability and rashes. On
examination, she was febrile, hypotensive and had a purpuric rash covering the face, trunk …

A 6-month-old girl with a 1-day history of fever and vomiting was admitted to hospital. She
was febrile and had mild dehydration. Within 4 h of admission, petechiae developed on the …

Apreviously healthy 62-year-old man presented to the emergency department with 4 days of
headache, fever, and chills. Within several hours of presentation, he developed septic …

We report the case of an 18-year-old immunocompetent man who presented to the hospital
with fever, headaches, and arthromyalgia, which progressed to include an erythematous …

Acute meningococcemia is characterized by extensive purpurae consisting of both
petechiae and ecchymoses. This condition can be rapidly fatal without treatment due to …

Acute infectious purpura fulminans (AIPF) is a rare, life-threatening disease commonly
caused by Neisseria meningitidis and Streptococcus pneumoniae. Gram-negative rods are …

The development of progressive, severe skin changes (purpura fulminans) is a serious
complication of septicaemia, particularly meningococcal septicaemia. Purpura fulminans …

In patients with meningococcal infection, devastating presentations, such as purpura
fulminans, which can progress to extensive tissue necrosis of the limbs and digits, have a …

In five patients with purpura fulminans following meaingitis, gangrene of the extremities
developed. Four patients required amputations of the lower extremities and two patients of …