Background: There is evidence that 2 classes of antihypertensive drugs may improve bone
mineral content. Animal studies have suggested that β-adrenergic blockers can increase …

ContextAnimal studies suggest that the β-blocker propranolol increases bone formation, but
data on whether use of β-blockers (with or without concomitant use of thiazide diuretics) is …

Objective. To quantitatively pool findings from observational studies on the risk of fracture
outcomes associated with exposure to five antihypertensive drug classes: angiotensin …

Thiazide diuretics have long been widely used as antihypertensive agents. In addition to
reducing blood pressure, thiazides also control calcium homeostasis and increase bone …

Osteoporosis, a common disease today, has serious impacts on both patients and society,
because prognosis can be complicated and therapy costly. It is therefore important to identify …

Abstract Purpose of Review This review summarizes the impact of thiazide diuretics on
fracture risk in older hypertensive individuals. Recent Findings We performed a post hoc …

Many medications used to control blood pressure have been associated with bone
metabolism. In addition, hypertension itself may be associated with reduced bone mineral …

Use of β-blockers is associated with a reduced risk of fractures in middle-aged and older
subjects from the general population. Introduction The present prospective population …

Objective: To investigate whether treatment with thiazide diuretics reduces the risk of
osteoporotic fractures in hypertensive patients in primary health care. Further we aimed to …

Background Cardiovascular diseases are associated with disturbances in calcium
metabolism, including increased urinary calcium, vitamin D insufficiency, and decreased …