Herpes simplex virus type 1 (HSV1) is present in latent form in the brains of a high
proportion of elderly people1 and is a risk factor for Alzheimer's disease in carriers of the …

Herpes simplex virus type 1 (HSV1) is present in latent form in the brains of a high
proportion of elderly people1 and is a risk factor for Alzheimer's disease in carriers of the …

In 1913, Noguchi and Moore [1] used the Levaditi silver staining method to identify
Treponema pallidum in 12 of 70 postmortem brains of patients with general paresis from the …

There is ongoing debate as to whether common viruses such as herpes simplex virus type 1
(HSV1) contribute to the aetiopathology of Alzheimer's disease (AD)[1]. We therefore …

Background The apolipoprotein E ε4 (APOE-ε4) allele is a risk factor for Alzheimer's disease
(AD), but it is neither essential nor sufficient for development of the disease. Other factors …

Herpes simplex encephalitis (HSE) is a rare but very serious disorder caused by herpes
simplex type 1 virus (HSV-1). Treatment with acyclovir decreases mortality but many patients …

Interest in the possible role of herpes simplex virus type 1 (HSV1) as a cofactor in the
pathogenesis of Alzheimer's disease (AD) has re-emerged following the detection of viral …

Itzhaki and colleagues (Jan 25, p 241) report that the combination of herpes simplex virus
type 1 (HSV1) in the brain and carriage of the apolipoprotein E ɛ 4 (APOE-ɛ4) allele is a …

This review describes investigations of specific topics that lie within the general subject of
HSV1's role in AD/dementia, published in the last couple of years. They include studies on …

To the Editor: We were interested to read the paper by Aiello et al. 1 on cytomegalovirus
(CMV) antibody levels and cognitive decline. It fits wellFas the authors point outFwith our …