[PDF][PDF] HIV clinical trials are not enough

ME Millson, AR Rachlis - CMAJ, 1999 - Can Med Assoc
© 1999 Canadian Medical Association representativeness, because the care is
administered by specific providers and may in some instances be provided to a specific …

Treatment of HIV/AIDS: do the dilemmas only increase?

MA Sande, A Ronald - JAMA, 2004 - jamanetwork.com
PHYSICIANS AND OTHER HEALTH CARE PROFESSIONALS who treat patients with
human immunodeficiency virus (HIV)/AIDS are confronted daily with complex challenges …

Rates of disease progression according to initial highly active antiretroviral therapy regimen: a collaborative analysis of 12 prospective cohort studies

Antiretroviral Therapy Cohort … - The Journal of infectious …, 2006 - academic.oup.com
Background No large clinical end-point trials have been conducted comparing regimens
among human immunodeficiency virus type 1–positive persons starting antiretroviral …

Therapeutic trials in HIV infection: which benefits for which patients?

L Piroth, JY Callerot, M Grappin, M Duong… - HIV Clinical …, 2001 - Taylor & Francis
Purpose: The purpose of our study was to make an assessment of the HIV patients' overall
opinion of therapeutic trials, to analyze the motivations and the reasons linked to this …

Comparative effectiveness of initial antiretroviral therapy regimens: ACTG 5095 and 5142 clinical trials relative to ART-CC cohort study

MJ Mugavero, M May, HJ Ribaudo… - JAIDS Journal of …, 2011 - journals.lww.com
Background The generalizability of antiretroviral therapy (ART) clinical trial efficacy findings
to routine care settings is not well studied. We compared the relative effectiveness of initial …

Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel

PG Yeni, SM Hammer, CCJ Carpenter, DA Cooper… - Jama, 2002 - jamanetwork.com
ObjectiveNew information warrants updated recommendations for the 4 central issues in
antiretroviral therapy: when to start, what drugs to start with, when to change, and what to …

Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society–USA panel

SM Hammer, MS Saag, M Schechter, JSG Montaner… - Jama, 2006 - jamanetwork.com
ContextGuidelines for antiretroviral therapy are important for clinicians worldwide given the
complexity of the field and the varied clinical situations in which these agents are used. The …

Use of observational databases to evaluate the effectiveness of antiretroviral therapy for HIV infection: comparison of cohort studies with randomized trials

AN Phillips, S Grabar, JM Tassie, D Costagliola… - Aids, 1999 - journals.lww.com
Objectives: It is important to assess the extent of bias when comparing the clinical efficacy of
antiretroviral regimens in observational databases because, with the current lack of planned …

Comparison of the effectiveness of non-nucleoside reverse transcriptase inhibitor-containing and protease inhibitor-containing regimens using observational …

AC Ghani, WE Henley, CA Donnelly, S Mayer… - Aids, 2001 - journals.lww.com
Objectives To compare the effectiveness of first protease inhibitor (PI)-containing and non-
nucleoside reverse transcriptase inhibitor (NNRTI)-containing regimens. Methods Data were …

[PDF][PDF] Scaling up treatment-why we can't wait

JY Kim, C Gilks - New England Journal of Medicine, 2005 - academia.edu
Many arguments have been raised over the years to justify not moving rapidly forward with
antiretroviral treatment programs for people living with the human immunodeficiency virus …