CMAJ| JANUARY 18, 2021| VOLUME 193| ISSUE 3 E95 leukopenia when taken
concurrently with azathioprine. 1 However, this association has exclusively been reported in …

Azathioprine (AZA) is a commonly used immunosuppressant in organ-transplantation
recipients. AZA is rapidly converted to 6-mercaptopurine and subsequently converted to 6 …

1Department of Gastroenterology and Hepatology, VU University Medical Centre,
Amsterdam, the Netherlands, 2Laboratory Genetic Metabolic Diseases, Academic Medical …

A 59-year-old female underwent a renal transplant in early 2015. Her initial
immunosuppression regimen was mycophenolate mofetil, prednisolone and tacrolimus. The …

Discussion: Altering the function of TMPT and XO can lead to high 6-TGN levels, which is
cleared from the body by TPMT. Concomitant use of allopurinol and AZA causes synergistic …

I welcome Salem and colleagues recent article on Azathioprine induced cholestatic hepatitis
[1]. Azathioprine is an immunosuppressant used in the management of a number of clinical …

Dear Editor, A 46-year-old Chinese male patient was diagnosed with autoimmune hepatitis—
primary biliary cholangitis overlap syndrome at the first admission on Apr 22nd 2016. He …

The thiopurines, azathioprine and 6-mercaptopurine (6-MP), are immunosuppressive drugs
used in a number of clinical settings, such as following transplantation and for the …

Azathioprine (AZA) is an immunosuppressant that is widely used to treat many disease
states including rheumatoid arthritis. We present a patient who was treated with AZA for …

Purpose: Case: An 89-year-old woman was admitted for syncope and generalized rash. The
rash started one week prior to admission and was accompanied by a fever. One month prior …