Studies have shown that for women who have taken vitamin supplements containing this
compound around the time of conception, the risk of a disturbance in early fetal development …

Neural tube defects occur within the first 4 weeks of conception when the neural tube in the
embryo does not close properly, resulting in the fetus developing spina bifida, anencephaly …

Background Periconceptional use of vitamin supplements containing folic acid reduces the
risk of a neural tube defect (NTD). In November 1998, food fortification with folic acid was …

Many countries, including the USA and Canada, have implemented fortification of foods with
folic acid, however the British Government only issues advice that supplements should be …

QUESTION Now that flour and pasta have been fortified with folic acid in Canada, do I still
need to recommend folic acid supplements to my patients who are of child-bearing age? If I …

If women relied only on dietary intake, a substantial proportion of the childbearing
population would receive a lower level of folic acid than is recommended for preventing …

Objective To provide information regarding the use of folic acid in combination with a
multivitamin supplement for the prevention of neural tube defects and other congenital …

Folic acid is the synthetic form of folate, a B vitamin found naturally in food. Folate and folic
acid are considered to influence the normal structural development of the embryo …

In the early 1990s two randomized clinical trials showed that folic acid, or multivitamins
containing folic acid, could substantially reduce a woman's risk of bearing a child with a …

We would not be allowed to conduct a clinical trial of a drug without proper monitoring
procedures for both expected and unexpected outcomes; however, such a scenario …