Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials

KZ Vardakas, II Siempos, A Grammatikos, Z Athanassa… - Cmaj, 2008 - Can Med Assoc
Background: We investigated whether the use of respiratory fluoroquinolones was
associated with better clinical outcomes compared with the use of macrolides and β-lactams …

Fluoroquinolone treatment of community-acquired pneumonia: a meta-analysis

AR Salkind, PG Cuddy… - Annals of …, 2002 - journals.sagepub.com
OBJECTIVE: To determine the role of newer fluoroquinolones (FQs) for adults with
community-acquired pneumonia (CAP) whose level of illness allows treatment with an oral …

Fluoroquinolones in the management of community‐acquired pneumonia

TE Albertson, NC Dean, AA El Solh… - … journal of clinical …, 2010 - Wiley Online Library
Aims: Review of the current guidelines for the use of respiratory fluoroquinolones in the
management of community‐acquired pneumonia (CAP). Methods: Data were collected from …

Fluoroquinolones or macrolides alone versus combined with β-lactams for adults with community-acquired pneumonia: Systematic review and meta-analysis

A Raz-Pasteur, D Shasha, M Paul - International journal of antimicrobial …, 2015 - Elsevier
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality. This
review compared two of the main treatment alternatives: quinolone or macrolide …

Fluoroquinolones in the management of community-acquired pneumonia in primary care

B Wispelwey, KR Schafer - Expert Review of Anti-infective Therapy, 2010 - Taylor & Francis
A literature search was conducted to evaluate the pharmacokinetic and pharmacodynamic
profile of the respiratory fluoroquinolones (gemifloxacin, levofloxacin and moxifloxacin) and …

Association between initial route of fluoroquinolone administration and outcomes in patients hospitalized for community-acquired pneumonia

RK Belforti, T Lagu, S Haessler… - Clinical Infectious …, 2016 - academic.oup.com
Background. Fluoroquinolones have equivalent oral and intravenous bioavailability, but
hospitalized patients with community-acquired pneumonia (CAP) generally are treated …

[HTML][HTML] Fluoroquinolones or macrolides in combination with β-lactams in adult patients hospitalized with community acquired pneumonia: a systematic review and …

KZ Vardakas, KK Trigkidis, ME Falagas - Clinical Microbiology and …, 2017 - Elsevier
Objective The best treatment option for hospitalized patients with community-acquired
pneumonia (CAP) has not been defined. The effectiveness of β-lactam/fluoroquinolone …

Pharmacokinetics and pharmacodynamics of fluoroquinolones in the respiratory tract

R Wise, D Honeybourne - European Respiratory Journal, 1999 - Eur Respiratory Soc
Pharmacokinetic and pharmacodynamic features are important predictors of the therapeutic
efficacy of an antibiotic. In respiratory tract infection, study of the clinical implication of …

Effectiveness of oral moxifloxacin in standard first-line therapy in community-acquired pneumonia

A Torres, JF Muir, P Corris, R Kubin… - European …, 2003 - Eur Respiratory Soc
Based on recent guidelines for the management of community-acquired pneumonia, this
study was designed to evaluate the effectiveness of a new fluoroquinolone compared with …

A review of new fluoroquinolones: focus on their use in respiratory tract infections

GG Zhanel, S Fontaine, H Adam, K Schurek… - Treatments in respiratory …, 2006 - Springer
The new respiratory fluoroquinolones (gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin,
and on the horizon, garenoxacin) offer many improved qualities over older agents such as …