Background: Although a convenient opioid delivery system, transdermal fentanyl patches
have caused several deaths and resulted in safety warnings reminding prescribers that …

CMAJ, June 14, 2016, 188 (9) 639 although fluctuations may occur up to 72 hours after
initiation. 2, 7 This delay to onset and peak is due to the need for the applied fentanyl to …

PROBLEM: Despite warnings from the FDA, drug manufacturers, and patient safety
agencies, fentanyl transdermal patches continue to be prescribed inappropriately to treat …

Purpose Although guidelines caution against initiation of transdermal (TD) fentanyl among
those who are opioid naïve, there is concern that not all people receive adequate prior …

Fentanyl transdermal system is indicated for the management of persistent, moderate-to-
severe chronic pain that requires continuous opioid administration for an extended period of …

Report No. 1: A nurse practitioner's 77-year-old family member died after a fentanyl patch
was incorrectly prescribed and subsequently misused. A week before the death, the family …

Answer: You and many other practitioners have found adjusting the dosage of transdermal
fentanyl to be cumbersome and time-consuming. The package insert for Duragesic (Janssen …

Purpose Fentanyl is a synthetic opioid available therapeutically as an intravenous,
transbucal, or transdermal preparation. It is also used as a drug of abuse through a variety of …

Background The current opioid overdose epidemic affecting communities across North
America is increasingly driven by illicitly manufactured fentanyl and its related analogues. A …

Am J Health-Syst Pharm. 1997; 54: 85-6 entanyl is a potent opioid that has been abused
both on the street and by health care professionals. 1-3 The transdermal delivery system for …