[HTML][HTML] Pregnancy and isotretinoin therapy
JS Choi, G Koren, I Nulman - Cmaj, 2013 - Can Med Assoc
Discussion Oral isotretinoin was introduced in the United States in 1982 and in Canada in
1983 for the treatment of severe recalcitrant acne. In the intervening decades, additional off …
1983 for the treatment of severe recalcitrant acne. In the intervening decades, additional off …
[HTML][HTML] A pregnancy-prevention program in women of childbearing age receiving isotretinoin
AA Mitchell, CM Van Bennekom… - New England Journal of …, 1995 - Mass Medical Soc
Background Isotretinoin is effective in treating severe acne, but it is also teratogenic. To
minimize pregnancies among exposed women, the manufacturer, together with the US Food …
minimize pregnancies among exposed women, the manufacturer, together with the US Food …
Safety issues in isotretinoin therapy.
N Hanson, S Leachman - Seminars in cutaneous medicine and …, 2001 - europepmc.org
Isotretinoin (Accutane, Roche Laboratories Inc, Nutley, NJ) is an important drug, not only for
the treatment of severe acne, but also for other diagnoses and in chemoprevention settings …
the treatment of severe acne, but also for other diagnoses and in chemoprevention settings …
[PDF][PDF] A review of systemic retinoid therapy for acne and related conditions
RA Kunynetz - Skin Therapy Lett, 2004 - Citeseer
Oral isotretinoin, since its introduction more than 20 years ago, has been and still is the “gold
standard” in the treatment of acne and its variants. This is the only approach to acne with the …
standard” in the treatment of acne and its variants. This is the only approach to acne with the …
[HTML][HTML] Isotretinoin; A review on the utilization pattern in pregnancy
S Khiali, A Gharekhani… - Advanced Pharmaceutical …, 2018 - ncbi.nlm.nih.gov
Purpose: Isotretinoin is the most effective anti-acne drug with a long-term remission.
However; it contains severe teratogenic effects with serious adverse drug reactions, which …
However; it contains severe teratogenic effects with serious adverse drug reactions, which …
A comparative review of the isotretinoin pregnancy risk management programs across four continents
T Kovitwanichkanont, T Driscoll - International Journal of …, 2018 - Wiley Online Library
Isotretinoin has revolutionized the treatment of severe acne vulgaris, a condition which if left
untreated may result in significant socio‐psychological implications for those affected …
untreated may result in significant socio‐psychological implications for those affected …
Isotretinoin revisited.
AR Shalita, RB Armstrong, JJ Leyden, PE Pochi… - Cutis, 1988 - europepmc.org
Isotretinoin (13-cis-retinoic acid) remains the drug of choice for treatment of severe,
recalcitrant nodulocystic acne that is unresponsive to conventional therapy, including oral …
recalcitrant nodulocystic acne that is unresponsive to conventional therapy, including oral …
When a uniquely effective drug is teratogenic
RS Stern - New England Journal of Medicine, 1989 - Mass Medical Soc
Isotretinoin is a uniquely effective oral agent for the treatment of severe cystic acne. 1
Typically a patient uses the medicine for 20 weeks, and in most cases enters a prolonged …
Typically a patient uses the medicine for 20 weeks, and in most cases enters a prolonged …
Adverse effects of isotretinoin: A retrospective review of 1743 patients started on isotretinoin
M Rademaker - Australasian Journal of Dermatology, 2010 - Wiley Online Library
ABSTRACT Background/Objectives: Isotretinoin has revolutionized the management of acne
vulgaris. However, concerns continue regarding the adverse effect profile of isotretinoin …
vulgaris. However, concerns continue regarding the adverse effect profile of isotretinoin …
Epidemiology of isotretinoin exposure during pregnancy
WS Dai, JM LaBraico, RS Stern - Journal of the American Academy of …, 1992 - Elsevier
Background: Exposure to isotretinoin during pregnancy is associated with a high risk of
major fetal malformations. Objective: Our purpose was to determine the reasons for and …
major fetal malformations. Objective: Our purpose was to determine the reasons for and …