Three patterns of minocycline-induced pigmentation have been described. 1 Type I results
in blue-black macules localized to areas of active inflammation or scarring. This type …

Sir, Skin pigmentation as a complication of minocycline therapy is familiar to dermatologists
but is less well recognized in general practice where the treatment is widely prescribed …

In four cases of minocycline hydrochloride-induced cutaneous pigmentation, blue-gray
discoloration in sites of cutaneous inflammation was seen in all cases. An additional finding …

Minocycline-induced cutaneous and nail bed discoloration, although uncommon, should be
closely watched for during treatment. The initial changes may be subtle and may mimic other …

The recent literature contains sporadic mention of localized pigmentary accumulations in
skin, bones, teeth, and thyroid tissue, presumably related to the use of systemic minocycline …

• Skin biopsy specimens and discolored fingernails from minocycline-treated patients were
examined by light and electron microscopy, histochemistry, and energy-dispersive x-ray …

Two patients receiving minocycline developed blue‐black pigmentation on the legs.
Biopsies from the pigmented areas demonstrated granules containing iron, a pigment with …

Minocycline‐induced nail pigmentation is an uncommon side‐effect. It usually develops after
years of the therapy, and coincides with other pigmented sites. We report a 73‐year‐old …

• Localized brown to blue-black discoloration of the skin occurred in three patients receiving
long-term minocycline hydrochloride therapy. Abundant perivascular pigmented material …

In the armamentarium of systemic antimicrobials used to treat the more severe forms of
acne, minocycline holds a prominent position. Generally considered more effective than the …