Background: Recent guidelines suggest lowering the target blood pressure for patients with
chronic kidney disease, although the strength of evidence for this suggestion has been …

Importance Trials in patients with hypertension have demonstrated that intensive blood
pressure (BP) lowering reduces the risk of cardiovascular disease and all-cause mortality …

There is controversy regarding whether strict blood pressure control is indicated in chronic
kidney disease (CKD) since the primary results of randomized controlled trials failed to show …

Objective To define the cardiovascular effects of lowering blood pressure in people with
chronic kidney disease. Design Collaborative prospective meta-analysis of randomised …

Background Recent hypertension guidelines have reversed previous recommendations for
lower blood pressure targets in high-risk patients, such as those with cardiovascular …

Background In observational studies, the relationship between blood pressure and end-
stage renal disease (ESRD) is direct and progressive. The burden of hypertension-related …

Importance The optimal blood pressure (BP) target remains debated in nondiabetic patients
with chronic kidney disease (CKD). Objective To compare intensive BP control (< 130/80 …

Background Guidelines recommend intensive blood pressure (BP) lowering in patients at
high risk. While placebo-controlled trials have demonstrated 22% reductions in coronary …

BP control is critical in the treatment of patients with chronic kidney disease. Recent
guidelines now recommend a BP goal of< 130/80 mmHg. Clinical trials using a randomized …

Background: The optimal blood pressure target in patients with chronic kidney disease
(CKD) is unclear. Purpose: To summarize trials comparing lower versus higher blood …