Treatment using thyroxine (LT4) in women who are pregnant and have slightly elevated
thyroid-stimulating hormone (TSH) remains controversial. Deshauer and Wyne1 provide …

Background: Evidence regarding subclinical hypothyroidism (SCH) effects on pregnancy
and the benefits of levothyroxine (LT4) treatment is inconsistent. The American Thyroid …

Objective To review the diagnosis and management of hypothyroidism during pregnancy, in
the preconception period, and in the postpartum period. Methods A literature review of …

Hypothyroidism occurs in approximately 3% of pregnant women and isolated
hypothyroxinemia in up to 8%(1, 2). Even mildly low maternal thyroxine (T4)(3, 4) and/or …

Hypothyroidism is a relatively common finding during pregnancy. This may be due either to
the presence of existing thyroid disease and/or to the increased demands that pregnancy …

The 2017 American Thyroid Association guidelines for the diagnosis and management of
thyroid disease during pregnancy and the postpartum were published six years after the …

Background There is a large body of evidence that suggests that subclinical hypothyroidism
during pregnancy is associated with a higher risk of adverse pregnancy outcomes. In current …

Overt hypothyroidism in pregnancy, defined as an elevated serum thyroid-stimulating
hormone (TSH) and reduced serum free thyroxine or a TSH> 10 mIU/L, is known to have …

This issue of the JCEM presents new guidelines for addressing thyroid dysfunction during
pregnancy and the postpartum period (1). These guidelines follow on those published 5 yr …

Diagnosing and treating thyroid disease during pregnancy is complex. For diagnosis,
knowledge of changes in thyroid hormone levels during pregnancy in general, and by …