The best type of trial
JAC Delaney - CMAJ, 2004 - Can Med Assoc
1. Jureidini JN, Doecke CJ, Mansfield PR, Haby MM, Menkes DB, Tonkin AL. Efficacy and
safety of antidepressants for children and adolescents. BMJ 2004; 328: 879-83. 2 …
safety of antidepressants for children and adolescents. BMJ 2004; 328: 879-83. 2 …
The best type of trial
MR Pijak, F Gazdik, S Hrusovsky - CMAJ, 2004 - Can Med Assoc
1. Jureidini JN, Doecke CJ, Mansfield PR, Haby MM, Menkes DB, Tonkin AL. Efficacy and
safety of antidepressants for children and adolescents. BMJ 2004; 328: 879-83. 2 …
safety of antidepressants for children and adolescents. BMJ 2004; 328: 879-83. 2 …
[HTML][HTML] Antidepressants for depressive disorder in children and adolescents: a database of randomised controlled trials
Y Zhang, X Zhou, J Pu, H Zhang, L Yang, L Liu, C Zhou… - BMC psychiatry, 2018 - Springer
Background In recent years, whether, when and how to use antidepressants to treat
depressive disorder in children and adolescents has been hotly debated. Relevant evidence …
depressive disorder in children and adolescents has been hotly debated. Relevant evidence …
[HTML][HTML] Facing the evidence: antidepressant treatment in children and adolescents
EJ Garland - Cmaj, 2004 - Can Med Assoc
Depression in childhood and adolescence is a chal-lenging problem for those affected, their
parents and their physicians. Before reaching the age of 18, about 1 in 5 young people will …
parents and their physicians. Before reaching the age of 18, about 1 in 5 young people will …
Clinical guidelines vs. clinical trials
G Emslie - Journal of Child and Adolescent Psychopharmacology, 2004 - liebertpub.com
An important issue for clinicians is to differentiate between clinical guidelines and clinical
trials. Clinical guidelines are developed from the research evidence, including randomized …
trials. Clinical guidelines are developed from the research evidence, including randomized …
28 Reanalysis of the treatment for adolescents with depression study (TADS) under the restoring invisible and abandoned trials initiative (RIAT)
Objectives Increasing numbers of children and adolescents are being prescribed
antidepressants, despite uncertainty about the benefits and harms. A majority of …
antidepressants, despite uncertainty about the benefits and harms. A majority of …
Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data
CJ Whittington, T Kendall, P Fonagy, D Cottrell… - The lancet, 2004 - thelancet.com
Background Questions concerning the safety of selective serotonin reuptake inhibitors
(SSRIs) in the treatment of depression in children led us to compare and contrast published …
(SSRIs) in the treatment of depression in children led us to compare and contrast published …
[HTML][HTML] Depression in children and adolescents
P Hazell - BMJ clinical evidence, 2009 - ncbi.nlm.nih.gov
Results We found 18 systematic reviews, RCTs, or observational studies that met our
inclusion criteria. We performed a GRADE evaluation of the quality of evidence for …
inclusion criteria. We performed a GRADE evaluation of the quality of evidence for …
[HTML][HTML] Academia's failure to support systematic reviews
I Chalmers - The Lancet, 2005 - thelancet.com
The Lancet's Paper of the Year 2004 (Dec 18/25, p 2166) 1, 2 is a systematic review of
selective serotoninreuptake inhibitors in childhood depression. This is the latest …
selective serotoninreuptake inhibitors in childhood depression. This is the latest …
Developing interventions in child and adolescent mental health services: do we really know what works for whom?
E Kennedy - Clinical child psychology and psychiatry, 2015 - journals.sagepub.com
A recent Cochrane Review of psychological therapies and antidepressants for depression in
children and adolescents concludes 'on the basis of the available evidence, we do not know …
children and adolescents concludes 'on the basis of the available evidence, we do not know …