To the editor: I agree with the conclusion of Drs. Gregory W. Hammond and H. Grant Stiver
(Can Med Assoc J 118: 524, 1978) that combination therapy is often necessary in cases of …

The efficacy of combination antibiotics in vivo and in vitro was studied during an outbreak of
prosthetic endocarditis caused by Staphylococcus epidermidis in 10 patients. The epidemic …

Staphylococcus epidermidis endocarditis occurred four days following aortic valve
replacement with a Björk-Shiley prosthesis. Antimicrobial therapy, shown to be effective by …

Seventy-five episodes of prosthetic valve endocarditis from Staphylococcus epidermidis
were studied retrospectively. Methicillin-resistant isolates caused 53 (87%) of 61 infections …

Twenty-three patients with prosthetic valve endocarditis caused by methicillin-resistant
Staphylococcus epidermidis were studied retrospectively for assessment of the role of …

without evidence of heart failure, but a second echocardiogram and a 99mTc pyrophosphate
scan of the heart revealed no vegetations. Thegentamycin/clindamycin combination was …

Antibiotic therapy for staphylococcal endocarditis is based on in vitro susceptibility, antibiotic
efficacy in experimental endocarditis, and clinical experience. Native valve endocarditis due …

10 patients with serious infections caused by Staphylococcus epidermidis (8 cases of
endocarditis in non-prosthetic valves, 1 was complicated by osteomyelitis, 1 case of …

Endocarditis was produced in rabbits with a methicillin-resistant Staphylococcus epidermidis
isolate. Subpopulations resistant to other semisynthetic penicillins and cephalosporins were …

Staphylococcus epidermidis is frequently associated with infection of prosthetic heart valves,
prosthetic orthopedic devices, and neurosurgical shunts. Penicillinase-resistant …