Polypharmacy and clinical outcomes

HN Shen - CMAJ, 2015 - Can Med Assoc
I read with interest the article by Lu and colleagues1 which shows that quality indicators of
pharmacotherapy are associated with increased odds of admission to hospital, but reduced …

Assessing the harms of polypharmacy requires careful interpretation and consistent definitions

L Kouladjian, SN Hilmer, TF Chen… - British Journal of …, 2014 - ncbi.nlm.nih.gov
The article by Payne and colleagues [1] concludes 'Assumptions that polypharmacy is
always unsafe or harmful,... need to be reconsidered in the clinical context of the conditions …

Reducing polypharmacy: Evidence from a simple quality improvement initiative

MO Little, A Morley - Journal of the American Medical Directors …, 2013 - jamda.com
Polypharmacy and inappropriate medical use are common and difficult problems in the long
term care setting. Polypharmacy is dangerous and expensive. Of geriatric patients admitted …

[HTML][HTML] Response to: Assessing the harms of polypharmacy requires careful interpretation and consistent definitions

RA Payne, GA Abel, AJ Avery, SW Mercer… - British Journal of …, 2014 - ncbi.nlm.nih.gov
Kouladjian and colleagues [1] call for caution around the conclusion of our recent work in
BJCP that polypharmacy is not always hazardous [2]. They reference a number of papers …

[HTML][HTML] Going beyond the numbers–a call to redefine polypharmacy

CM Hughes, JA Cooper, C Ryan - British journal of clinical …, 2014 - ncbi.nlm.nih.gov
'Polypharmacy'has often been used to describe the use of multiple medications and has
been noted as 'one of the most pressing prescribing challenges'[1]. There is no accepted …

Potentially Inappropriate Medications and Polypharmacy

SW Lai - Journal of the American Medical Directors Association, 2018 - jamda.com
One cross-sectional study conducted by Anrys and colleagues 1 published in JAMDA has
reported that the prevalence of potentially inappropriate medications was 88.3% among …

Effect of polypharmacy, potentially inappropriate medications and anticholinergic burden on clinical outcomes: a retrospective cohort study

WH Lu, YW Wen, LK Chen, FY Hsiao - Cmaj, 2015 - Can Med Assoc
Background: Polypharmacy, potentially inappropriate medications and anticholinergic
burden (as assessed by the anticholinergic risk scale) are commonly used as quality …

Multimorbidity or polypharmacy: two sides of the same coin?

C Sinnott, CP Bradley - Journal of comorbidity, 2015 - journals.sagepub.com
Given the obvious overlap between the concepts of polypharmacy and multimorbidity, it is
striking that much of the research on these two issues is conducted in parallel, rather than in …

Is polypharmacy always hazardous? A retrospective cohort analysis using linked electronic health records from primary and secondary care

RA Payne, GA Abel, AJ Avery… - British journal of …, 2014 - Wiley Online Library
Aims Prescribing multiple medications is associated with various adverse outcomes, and
polypharmacy is commonly considered suggestive of poor prescribing. Polypharmacy might …

Polypharmacy

G Onder, A Marengoni - JAMA, 2017 - jamanetwork.com
This often happens when a person has many chronic diseases, such as diabetes, high
blood pressure, heart failure, osteoporosis, and/or symptoms such as pain or insomnia …