In addition to their essential role in fighting infection, T lymphocytes are proving their use in
eliminating cancer cells. This ability is at the heart of recent research into immunotherapy for …

In this review article we examine the role of inflammation-related genes in osteoarthritis (OA)
from the perspective of genetics, epigenetics and gene expression. There have been great …

In addition to their essential role in fighting infection, T lymphocytes are proving their use in
eliminating cancer cells. This ability is at the heart of recent research into immunotherapy for …

The largest study to date on the genetics of hip and knee osteoarthritis (OA) has yielded new
associations with genes encoding a cytokine, a kinase and a transcriptional repressor, as …

Rheumatoid arthritis is incurable and difficult to treat with traditional pharmacological
approaches. Because conventional drug therapy has clearly failed to conquer this …

Cover Page The handle http://hdl.handle.net/1887/33065 holds various files of this Leiden
University dissertation Author: Ramos, Page 1 Cover Page The handle http://hdl.handle.net/1887/33065 …

At the 2010 Osteoarthritis Research Society International (OARSI) congress in Brussels I
was asked to present on “Genetics” in the “Year in Review” session. This gave me an …

Completion of the Human Genome Project in 2003, an international effort to map all genes
in the human genome (1), brought forward the promise of identifying the genetic …

Purpose: Transcriptomics has been extensively used to explore genomic changes occurring
with osteoarthritis (OA). Animal models have also been used widely in the study of OA as pre …

Osteoarthritis (OA), a degenerative joint disease, increases in prevalence with age, and
affects majority of individuals over the age of 65. OA frequently affects several joints …