1130 CMAJ, October 21, 2014, 186 (15) put their lives on the line to help Liberians during an
uncontrolled, unprecedented outbreak, or two of the hundreds of Africans who might benefit …

West Africa is experiencing the largest, most severe, most complex outbreak of Ebola virus
disease in history. Previous Ebola outbreaks have been contained by existing interventions …

Ebola virus causes lethal hemorrhagic fever in human and nonhuman primates. Effective
prophylaxis and treatment for this disease are not yet available. Antisera and monoclonal …

Since it first appeared as a clinical syndrome in Central Africa in the mid-1970s
accompanied by isolation of the causative virus, Ebolavirus disease has fascinated …

Response to the current ebolavirus outbreak based on traditional control measures has so
far been insufficient to prevent the virus from spreading rapidly. This has led to urgent …

While several impeding factors have limited Ebola vaccine development, the current
epidemic has provided a surge which may lead to a record pace for a vaccine against Ebola …

With one investigational vaccine al ready deployed, officials are discussing the possibility of
introducing as many as six other preventive and therapeutic interventions in the midst of the …

Ebola virus infection is a highly lethal disease for which there are no effective therapeutic or
preventive treatments. Several vaccines have provided immune protection in laboratory …

Sporadic outbreaks of Ebola virus infection have been documented since the mid-Seventies
and viral exposure can lead to lethal haemorrhagic fever with case fatalities as high as 90 …

Ebola virus disease in humans is highly lethal, with case fatality rates ranging from 25 to
90%. There is no licensed treatment or vaccine against the virus, underscoring the need for …