Brief safety updates: acetaminophen, ASA and kava

E Wooltorton - CMAJ, 2002 - Can Med Assoc
Acetaminophen—unintentional overdoses: Accidental overdoses of acetaminophen are the
most common cause of acute liver failure in the United States. For this reason, the US Food …

Acetaminophen: old drug, new warnings.

A Schilling, R Corey, M Leonard… - Cleveland Clinic journal …, 2010 - europepmc.org
The US Food and Drug Administration (FDA), concerned about the incidence of acute liver
failure due to acetaminophen (Tylenol) overdose, has mandated new labeling on …

Moving the needle to reduce acetaminophen (paracetamol) hepatotoxicity

MG Ghany, PB Watkins - JAMA, 2023 - jamanetwork.com
Acetaminophen (paracetamol) is the most widely used pain reliever globally. It was
approved in the US in 1950 as a prescription drug and then for over-the-counter (OTC) use …

[PDF][PDF] Acetaminophen and the US Acute Liver Failure Study Group: lowering the risks of hepatic failure

WM Lee - Hepatology, 2004 - Wiley Online Library
Acetaminophen overdose is the leading cause for calls to Poison Control Centers (>
100,000/year) and accounts for more than 56,000 emergency room visits, 2,600 …

[PDF][PDF] Acetaminophen sets records in the United States: number 1 analgesic and number 1 cause of acute liver failure

JD Perkins - Liver transplantation, 2006 - Wiley Online Library
Severe acetaminophen hepatotoxicity frequently leads to acute liver failure (ALF). We
determined the incidence, risk factors, and outcomes of acetaminophen-induced ALF at 22 …

[HTML][HTML] Acetaminophen toxicity: what pharmacists need to know

EM Ambizas - US Pharm, 2014 - uspharmacist.com
Acetaminophen toxicity is one of the most common causes of both intentional and
unintentional poisoning in the United States. It has become the most common cause of acute …

FDA asks physicians to stop prescribing high-dose acetaminophen products

M Mitka - Jama, 2014 - jamanetwork.com
After only limited success in per-suadingdrugmanufacturerstoreduce the amount of the
painkiller acetaminophen in prescription combination products, the US Food and Drug …

Acetaminophen: Is it Time for a Change in Utilization to Decrease the Risk of Hepatotoxicity?

DE Baker - Hospital Pharmacy, 2009 - journals.sagepub.com
Acetaminophen (also known as APAP or paracetamol) has long been considered a safe
nonprescription analgesic and antipyretic. Furthermore, it is considered a safe alternative to …

Prescription acetaminophen ingestions associated with hepatic injury and death

RM Martinez, SP Nordt, FL Cantrell - Journal of community health, 2012 - Springer
Abstract The US Food and Drug Administration has formally requested that pharmaceutical
manufacturers limit the amount of acetaminophen (APAP) in prescription products. The goal …

The FDA Acetaminophen Advisory Committee Meeting–what is the future of acetaminophen in the United States? The perspective of a committee member

EP Krenzelok - Clinical Toxicology, 2009 - Taylor & Francis
Background. Unintentional acetaminophen toxicity is a common problem throughout the
world but particularly in the more developed countries. To deal with the problem, several …