The excipients and additives in drug formulations have been described as inert because
they do not have an active role in the prevention or treatment of particular ailments. This has …

Everyone who prescribes a modern formulated drug is aware of the risks of adverse
reactions due to the properties inherent in the active ingredients, but not all are aware of the …

Excipient reactions have resulted from the use of clearly toxic substances (eg
diethyleneglycol), the use of certain excipients in a susceptible group (eg very low …

Excipients are essential ingredients of medicinal products. Approximately 1000 excipients
are today in use in marketed pharmaceuticals. The safety issues regarding excipients can …

Concern arises for patients with diabetes mellitus consuming sucrose. Of total mass. oral
tablets may contain 5 to 20% sucrose. chewable tablets 20 to 60% sucrose. and some …

Formulation of a new drug product with excipients, that have been previously added to an
approved injectable product, may save pharmaceutical companies developmental time and …

The diagnosis and management of adverse reactions caused by excipients is hindered by
the restrictive attitudes of sections of the pharmaceutical industry and of some regulatory …

A medicine consists of 2 fundamental parts: the active pharmaceutical ingredient and the
excipient. Most, if not all, medicines could not be made without the use of excipients. In the …

In this article, the authors trace the evolution of the industry's opinions and developments
that have led to the current perception and use of excipients. From their initial use as inert …