The madness of King George III has been attributed to acute intermittent porphyria, an
inherited genetic disorder of the heme biosynthesis pathway. Acute attacks of porphyria …

The madness of King George III has been attributed to acute intermittent porphyria, an
inherited genetic disorder of the heme biosynthesis pathway. Acute attacks of porphyria …

Discussion There are four acute porphyrias, which are inheritable metabolic diseases. All
stem from discrete—and variably severe—enzymatic defects in the heme synthesis pathway …

Fast track to the porphyrias | Nature Medicine Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Porphyrias are a group of genetic disorders caused by mutations in enzymes of the heme
biosynthesis pathway. Acute attacks of porphyria, reputedly the disease that incapacitated …

Correction to: Medical and financial burden of acute intermittent porphyria | SpringerLink Skip
to main content Advertisement SpringerLink Log in Menu Find a journal Publish with us Search …

Acute intermittent porphyria (AIP) is an autosomal dominant genetic defect in heme
synthesis. Patients with this illness can have episodic life-threatening attacks characterized …

Acute intermittent porphyria (AIP) is a rare genetic metabolic disease caused by a specific
enzyme dysfunction in the hepatic heme biosynthesis pathway. Besides the obvious clinical …

To the Editor: In their article on a phase 3 trial of givosiran for the treatment of acute
intermittent porphyria, Balwani et al.(June 11 issue) 1 indicate that the drug may increase …

Alan Bennett's highly successful play and film The Madness of King George has re-
awakened the debate on whether the sovereign suffered with the haem metabolic disorder …