The medicinal use of marijuana goes back into history as far as several thousand years, by
some accounts. But it was in the 1800s that its potential as an analgesic began to be …

Cannabis extracts have been used medicinally for many thousands of years, including for
pain relief. The identification of the major psychoactive component of cannabis, delta-9 …

Historical accounts and anecdotal reports show that among the most common medicinal
uses of cannabis is pain relief [1]. Such accounts date back to the ancient Chinese physician …

176 British Journal of Anaesthesia| CEPD Reviews| Volume 3 Number 6 2003 which bind to
cannabinoid receptors and exhibit cannabimimetic effects. Classical cannabinoid effects in …

Many of the effects of cannabinoids are mediated by specific cannabinoid receptors, two
types of which have so far been identified: CB1, cloned in 1990, and CB2, cloned in 1993 (1 …

Cannabinoids have significant analgesic properties in animal models, particularly for
chronic pain states, but there are few human studies. An endogenous cannabinoid system …

In the popular press, many Canadians claim to be using herbal cannabis (marijuana) to
control symptoms such as pain, nausea, muscle spasm, anorexia and anxiety that may be …

The identification of cannabinoid receptors and the discovery of endogenous cannabinoids
ushered in a new era of research on the biological effects of cannabis-like compounds …

Recent advances have dramatically increased our understanding of cannabinoid
pharmacology: the psychoactive constituents of Cannabis sativa have been isolated …

Objective: To review the literature concerning the physiology of the endocannabinoid
system, current drug development of cannabinoid agonists, and current clinical research on …