Alpha1-antitrypsin phenotypes and lung function in a moderately polluted northern Ontario community.
DN Ostrow, J Manfreda, T Dorman… - Canadian Medical …, 1978 - ncbi.nlm.nih.gov
To determine whether persons with intermediate value alpha1-antitrypsin phenotypes living
in a polluted environment manifest significant abnormalities in lung function, a study was …
in a polluted environment manifest significant abnormalities in lung function, a study was …
Alpha 1-antitrypsin phenotypes and obstructive lung disease in the city of Oslo.
A Gulsvik, MK Fagerhol - Scandinavian journal of respiratory …, 1979 - europepmc.org
In a community survey in Oslo, Norway, comprising 1268 persons, alpha 1-antitrypsin
concentration in serum (AT) and protease-inhibitor (Pi) phenotypes were examined in 1258 …
concentration in serum (AT) and protease-inhibitor (Pi) phenotypes were examined in 1258 …
A Community Study of the Relation of Alpha1-Antitrypsin Levels to Obstructive Lung Diseases
JO Morse, MD Lebowitz, RJ Knudson… - New England Journal …, 1975 - Mass Medical Soc
Since it is still uncertain whether moderate degrees of alpha1-antitrypsin deficiency
predispose to the development of lung disease, data obtained from a stratified random …
predispose to the development of lung disease, data obtained from a stratified random …
Pulmonary abnormalities in intermediate alpha-1-antitrypsin deficiency.
WJ Hall, RW Hyde, RH Schwartz… - The Journal of …, 1976 - Am Soc Clin Investig
Pulmonary function studies were carried out in a group of asymptomatic nonsmoking adults
with intermediate alpha-1-antitrypsin deficiency who were attending an early disease …
with intermediate alpha-1-antitrypsin deficiency who were attending an early disease …
Relation of alpha-1-antitrypsin phenotype to the performance of pulmonary function tests and to the prevalence of respiratory illness in a working population.
RB Cole, NC Nevin, G Blundell, JD Merrett… - Thorax, 1976 - thorax.bmj.com
Individuals with severe alpha-1-antitrypsin (alpha1AT) deficiency (phenotype Pi ZZ) are
abnormally liable to develop emphysema, but it is uncertain whether those with partial …
abnormally liable to develop emphysema, but it is uncertain whether those with partial …
Lung Function in Alpha1-Antitrypsin Heterozygotes (Pi Type MZ)
DM Cooper, V Hoeppner, D Cox, N Zamel… - American Review of …, 1974 - atsjournals.org
Whether or not α1-antitrypsin heterozygotes are abnormally predisposed to lung disease is
controversial. To define the pulmonary status of the heterozygote Pi type MZ, results of lung …
controversial. To define the pulmonary status of the heterozygote Pi type MZ, results of lung …
Smoking and chronic obstructive lung disease in alpha1-antitrypsin deficiency
C Mittman, J Lieberman, F Marasso, A Miranda - Chest, 1971 - Elsevier
Similar spectra of chronic obstructive lung disease were observed in eight patients with
severe and 21 with intermediate alpha 1-antitrypsin deficiency, but patients with …
severe and 21 with intermediate alpha 1-antitrypsin deficiency, but patients with …
Pulmonary function in nonsmoking subjects with alpha1 antitrypsin deficiency (MZ phenotype)
AF Gelb, E Klein, J Lieberman - The American journal of medicine, 1977 - Elsevier
We measured pulmonary functions in 10 nonsmoking asymptomatic subjects, ages 40.5
years±9.2 years, with alpha 1 antitrypsin heterozygous deficiency (phenotype MZ). The …
years±9.2 years, with alpha 1 antitrypsin heterozygous deficiency (phenotype MZ). The …
Relation of protease inhibitor phenotypes to obstructive lung diseases in a community
JO Morse, MD Lebowitz, RJ Knudson… - New England Journal …, 1977 - Mass Medical Soc
To examine the relative risk for the development of obstructive lung disease in persons
heterozygous for alpha1-antitrypsin deficiency, we determined protease inhibitor …
heterozygous for alpha1-antitrypsin deficiency, we determined protease inhibitor …
Cardiopulmonary Function in α1-Antitrypsin Heterozygotes Exposed to Severe Air Pollution
A Szczeklik, K Stankowska, I Frydecka - American Review of …, 1973 - atsjournals.org
Homozygous deficiency of (II-antitrypsin has been shown to predispose to pulmonary
emphysema. t. 2 The inherited heterozygous condition, however, has not given clear-cut …
emphysema. t. 2 The inherited heterozygous condition, however, has not given clear-cut …