Use: The use of escalated doses of chemotherapy in patients with cancer is limited by toxic
effects on tissues such as the bone marrow. Irreversible damage to bone marrow and the …

High-dose chemotherapy and autologous bone marrow transplantation can be associated
with patients living disease-free with some cancers for long periods of time. However, all too …

A major concern in autologous bone marrow transplantation (ABMT) is the possible
contamination of the graft with tumor cells. Transplantation of malignant cells, along with …

Peripheral blood has replaced bone marrow as a source of hematopoietic stem cells for
autologous rescue after high‐dose chemotherapy. Patients who receive peripheral blood …

Since the development of chemotherapy, the treatment of patients with cancer has improved
remarkably. In most patients however, chemotherapy regimens alone are not sufficient to …

When bone marrow (BM) cryopreservation was introduced in the late sixties [36] and the first
autologous BM transplantation (ABMT) tested in the seventies [43], the general idea was that …

High-dose chemotherapy with haematopoietic stem cell rescue has proven to be an effective
treatment in relapsed lymphoma and neuroblastoma. This treatment approach should be …

Blood-derived stem cells are a functionally equivalent alternative to marrow-derived stem
cells when autotransplanted to restore hematopoiesis that has been iatrogenically ablated …

Autologous hematopoietic stem cell transplantation (HSCT) refers to the use of self-
renewing progenitor cells derived either from the patient's own marrow or peripheral blood …

I NTENSIVE chemoradiotherapy with autologous hema-topoietic progenitor cell support
(AHPCS) is being used with increasing frequency to treat patients with a variety of …