Ubiquitous preservative blamed for rash of skin allergies

C Cross - 2013 - Can Med Assoc
The British Association of Derma-tologists wants a ban on a preservative in products as
diverse as face powder, paint, body wash and baby wipes, blaming it for an “epidemic” of …

Methylisothiazolinone

MP Castanedo-Tardana, KA Zug - Dermatitis, 2013 - liebertpub.com
The preservative methylisothiazolinone (MI) is the American Contact Dermatitis Society
Contact Allergen of the Year for 2013. Because the use of MI in cosmetics and toiletries in …

Epidemic of isothiazolinone allergy in North America: prevalence data from the North American Contact Dermatitis Group, 2013–2014

MJ Zirwas, D Hamann, EM Warshaw, HI Maibach… - Dermatitis, 2017 - liebertpub.com
Background Preservative sensitivity patterns evolve with changing use patterns in products.
During the last decade, the use of methylisothiazolinone (MI) at higher concentrations in …

Trends in the prevalence of methylchloroisothiazolinone/methylisothiazolinone contact allergy in North America and Europe

MJ Reeder, E Warshaw, S Aravamuthan… - Jama …, 2023 - jamanetwork.com
Importance The common use of isothiazolinones as preservatives is a global cause of
allergic contact dermatitis. Differences in allowable concentrations of methylisothiazolinone …

[CITATION][C] The methylisothiazolinone epidemic: Is the fire out or is Rome still burning?

T Editors - Contact Dermatitis, 2014 - Wiley Online Library
The story of the epidemic of contact allergy to methylisothiazolinone (MI), a preservative
permitted up to 100 ppm in cosmetic products, is a sorry one. Clinical dermatologists gave …

American Contact Dermatitis Society contact allergy management program: an epidemiologic tool to quantify ingredient usage

A Scheman, D Severson - Dermatitis, 2016 - liebertpub.com
Background The usage prevalence of ingredients in topical products is important to
dermatologists and industry. Objective To determine the prevalence of …

[PDF][PDF] Methylisothiazolinone and isothiazolinone allergy

M Reeder, AR Atwater - Cutis, 2019 - cdn.mdedge.com
Background Methylchloroisothiazolinone (MCI) and MI have been utilized as a preservative
in a 3: 1 ratio since the 1980s. In 2005, MI was first used alone as a preservative in personal …

Trends in preservative allergy: Benzisothiazolinone emerges from the pack

N King, F Latheef, M Wilkinson - Contact Dermatitis, 2021 - Wiley Online Library
Background Preservatives are used widely in cosmetic, household, and industrial products
to prevent microbial growth and spoiling of the products. There has been a recent epidemic …

Recommendation to include methylisothiazolinone in the E uropean baseline patch test series–on behalf of the E uropean S ociety of C ontact Dermatitis and the E …

M Bruze, M Engfeldt, M Gonçalo… - Contact Dermatitis, 2013 - Wiley Online Library
Background Methylisothiazolinone (MI) is used as a preservative in occupational and
household products, and cosmetics. It is a part of the preparation of …

Benzisothiazolinone: new kid on the block

N King, M Wilkinson, F Latheef… - British Journal of …, 2021 - academic.oup.com
Preservatives are widely used in cosmetic, household and industrial products to prevent
microbial growth. There have been a number of epidemics of preservative allergy over the …