Inactivation of isoniazid by Canadian Eskimos and Indians
CWL Jeanes, O Schaefer, L Eidus - Canadian Medical Association …, 1972 - ncbi.nlm.nih.gov
Eskimos and Indians Page 1 ORIGINAL ARTICLES Inactivation of isoniazid by Canadian
Eskimos and Indians CWL Jeanes, md, O. Schaefer, md and L. Eidus, md, Ottawa, Ont. Summary …
Eskimos and Indians CWL Jeanes, md, O. Schaefer, md and L. Eidus, md, Ottawa, Ont. Summary …
Studies on isoniazid conversion in Thailand
W Schloot, KG Blume, HW Goedde, G Flatz… - Humangenetik, 1967 - Springer
Isoniazid inactivation was studied in a sample of 100 subjects from Central Thailand. The
frequency of the allele Ac S (resulting in “slow” inactivation in the homozygous state) was …
frequency of the allele Ac S (resulting in “slow” inactivation in the homozygous state) was …
Determination of the isoniazid acetylator phenotype in a West African population
LA Salako, AF Aderounmu - Tubercle, 1977 - Elsevier
The concentration of isoniazid in plasma after an oral dose of 10 mg/kg was estimated in
120 Nigerians (39 normal, 81 tuberculous). The concentrations were bimodally distributed …
120 Nigerians (39 normal, 81 tuberculous). The concentrations were bimodally distributed …
On phenotyping with isoniazid: the use of urinary acetylation ratio and the uniqueness of antimodes. Study of two Amerindian populations
T Inaba, TD Arias - Clinical Pharmacology & Therapeutics, 1987 - Wiley Online Library
Various conventions have been used to express the activity of polymorphic hepatic N‐
acetyltransferase of isoniazid. Among them, two of the most common are the “percentage of …
acetyltransferase of isoniazid. Among them, two of the most common are the “percentage of …
Determination of acetylator phenotype based on the ratio of acetylisoniazid to isoniazid in urine following an oral dose of ordinary isoniazid
G Raghupati Sarma, M Kannapiran… - Indian Journal of …, 1976 - eprints.nirt.res.in
A simple method for classifying subjects as slow or rapid inactivators of isoniazid has been
described. A uniform dose of 300 mg. of ordinary isoniazid was administered orally to 150 …
described. A uniform dose of 300 mg. of ordinary isoniazid was administered orally to 150 …
A simple method for determining acetylator phenotype using isoniazid.
A Hutchings, PA Routledge - British journal of clinical …, 1986 - Wiley Online Library
A comparison was made between the results of acetylator phenotyping by isoniazid (INH)
half‐life measurements based on samples taken for 6 h after a single oral dose (200 mg) …
half‐life measurements based on samples taken for 6 h after a single oral dose (200 mg) …
The frequency of isoniazid acetylase enzyme deficiency among Egyptians
N Hashem, S Khalifa, A Nour - American journal of physical …, 1969 - Wiley Online Library
The frequency of isoniazid slow inactivators is very high among Eqyptians, 82% have more
than 0.91 γ/ml of free INH in serum specimens obtained six hours after a single dose of 10 …
than 0.91 γ/ml of free INH in serum specimens obtained six hours after a single dose of 10 …
Incidence of isoniazid acetylation phenotypes in North Indians.
Isoniazid acetylation phenotypes were determined in 110 cases (55 of pulmonary
tuberculosis and 55 of nontubercular chest diseases) by sulphadimidine acetylation test …
tuberculosis and 55 of nontubercular chest diseases) by sulphadimidine acetylation test …
Determination of the acetylator phenotype from the ratio of the urinary excretion of acetylisoniazid to acid-labile isoniazid: a study in Finnish Lapland
GA Ellard, PT Gammon, H Tiitinen - Tubercle, 1973 - Elsevier
The concentrations of isoniazid, acid-labile isoniazid, acetylisoniazid, isonicotinic acid and
isonicotinylglycine were determined in the serum at 30, 60 and 90 min, and in the urine 0–3 …
isonicotinylglycine were determined in the serum at 30, 60 and 90 min, and in the urine 0–3 …
Isoniazid acetylation phenotyping in the Japanese: the molar metabolic ratio INH/AcINH
H Kohno, H Kubo, A Takada, M Mori… - American journal of …, 1996 - journals.lww.com
The N-acetylation phenotyping of isoniazid (INH) was studied in 434 unrelated Japanese
pulmonary tuberculosis patients. The frequency of slow acetylators was determined using …
pulmonary tuberculosis patients. The frequency of slow acetylators was determined using …