Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects

AD Furlan, JA Sandoval, A Mailis-Gagnon, E Tunks - Cmaj, 2006 - Can Med Assoc
Background: Chronic noncancer pain (CNCP) is a major health problem, for which opioids
provide one treatment option. However, evidence is needed about side effects, efficacy, and …

Opioids for chronic noncancer pain: a systematic review and meta-analysis

JW Busse, L Wang, M Kamaleldin, S Craigie, JJ Riva… - Jama, 2018 - jamanetwork.com
Importance Harms and benefits of opioids for chronic noncancer pain remain unclear.
Objective To systematically review randomized clinical trials (RCTs) of opioids for chronic …

Opioids in chronic non-cancer pain: systematic review of efficacy and safety

E Kalso, JE Edwards, RA Moore, HJ McQuay - Pain, 2004 - Elsevier
Opioids are used increasingly for chronic non-cancer pain. Controversy exists about their
effectiveness and safety with long-term use. We analysed available randomised, placebo …

[HTML][HTML] Long-term opioid therapy for chronic noncancer pain: a systematic review and meta-analysis of efficacy and safety

M Noble, SJ Tregear, JR Treadwell… - Journal of pain and …, 2008 - Elsevier
Opioid therapy for chronic noncancer pain (CNCP) is controversial due to concerns
regarding long-term efficacy and adverse events (including addiction). We systematically …

Analgesic efficacy of opioids in chronic pain: recent meta‐analyses

H Reinecke, C Weber, K Lange… - British journal of …, 2015 - Wiley Online Library
Opioids are regularly administered in acute and cancer pain. In chronic non‐cancer pain
(CNCP), however, their use is controversial. Previous meta‐analyses and randomized …

[PDF][PDF] A systematic review of randomized trials of long-term opioid management for chronic non-cancer pain

L Manchikanti, H Ailinani, D Koyyalagunta… - Pain …, 2011 - researchgate.net
Background: Even though opioids have been used for pain for thousands of years, opioid
therapy for chronic non-cancer pain is controversial due to concerns regarding the long-term …

European* clinical practice recommendations on opioids for chronic noncancer pain–Part 1: Role of opioids in the management of chronic noncancer pain

W Häuser, B Morlion, KE Vowles… - … Journal of Pain, 2021 - Wiley Online Library
Background Opioid use for chronic non‐cancer pain (CNCP) is complex. In the absence of
pan‐European guidance on this issue, a position paper was commissioned by the European …

[HTML][HTML] Research gaps on use of opioids for chronic noncancer pain: findings from a review of the evidence for an American Pain Society and American Academy of …

R Chou, JC Ballantyne, GJ Fanciullo, PG Fine… - The Journal of …, 2009 - Elsevier
Chronic noncancer pain is common and use of opioids is increasing. Previously published
guidelines on use of opioids for chronic noncancer pain have been based primarily on …

Risk-benefit assessment of opioids in chronic noncancer pain

B Bannwarth - Drug safety, 1999 - Springer
Opioids have been accepted as appropriate treatment for acute and cancer pain, but their
role in the management of chronic nonmalignant pain is the subject of much debate, mainly …

Opioids in chronic non-cancer pain, indications and controversies

H Breivik - European Journal of pain, 2005 - Elsevier
The use of opioid analgesics for long term management of chronic non-cancer pain is now
an accepted, although still a controversial medical practice. In some well selected patients …