An-Wen Chan and associates, 1 in their evaluation of outcome reporting bias in 48
randomized controlled trials funded by the Canadian Institutes of Health Research (CIHR) …

Background: The reporting of outcomes within published randomized trials has previously
been shown to be incomplete, biased and inconsistent with study protocols. We sought to …

OBJECTIVE: To assess outcome reporting bias and dissemination bias in trials funded by
the National Health System (NHS) Health Technology Assessment (HTA) program. STUDY …

REPORTS OF RANDOMIZED controlled trials (RCTs) have become the “gold standard” by
which health care professionals make decisions about the effectiveness of most …

PURPOSE We wanted to investigate the frequency of undisclosed changes in the outcomes
of randomized controlled trials (RCTs) between trial registration and publication. METHODS …

Context Previous studies indicate that the interpretation of trial results can be distorted by
authors of published reports. Objective To identify the nature and frequency of distorted …

Overwhelming evidence now indicates that the quality of reporting of randomized, controlled
trials (RCTs) is less than optimal. Recent methodologic analyses indicate that inadequate …

This is not our only obligation, however. In Western societies, medical product development
is left to the marketplace, not to academia or government agencies. 29 For drugs and …

This is an important sentiment and has been echoed by patient advocacy groups who hold
that clinical trial registration and results reporting are important and necessary steps to …

Patient reported outcomes are key variables in clinical research, but it is not always easy to
select the best methods to measure them in specific situations. We welcome, therefore, in …