Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1 diabetes: a randomized crossover controlled trial
Background: Most patients with type 1 diabetes do not achieve their glycemic targets. We
aimed to assess the efficacy of glucose-responsive insulin and glucagon closed-loop …
aimed to assess the efficacy of glucose-responsive insulin and glucagon closed-loop …
Glucose-responsive insulin delivery for type 1 diabetes: The artificial pancreas story
Insulin replacement therapy is integral to the management of type 1 diabetes, which is
characterised by absolute insulin deficiency. Optimal glycaemic control, as assessed by …
characterised by absolute insulin deficiency. Optimal glycaemic control, as assessed by …
Comparison of dual-hormone artificial pancreas, single-hormone artificial pancreas, and conventional insulin pump therapy for glycaemic control in patients with type …
Background The artificial pancreas is an emerging technology for the treatment of type 1
diabetes and two configurations have been proposed: single-hormone (insulin alone) and …
diabetes and two configurations have been proposed: single-hormone (insulin alone) and …
Single-and dual-hormone artificial pancreas for overnight glucose control in type 1 diabetes
Context: The added benefit of glucagon in artificial pancreas systems for overnight glucose
control in type 1 diabetes has not been fully explored. Objective: The objective of the study …
control in type 1 diabetes has not been fully explored. Objective: The objective of the study …
Closed loop insulin delivery in diabetes
T Battelino, JŠ Omladič, M Phillip - Best Practice & Research Clinical …, 2015 - Elsevier
The primary goal of type 1 diabetes treatment is attaining near-normal glucose values. This
currently remains out of reach for most people with type 1 diabetes despite intensified insulin …
currently remains out of reach for most people with type 1 diabetes despite intensified insulin …
The artificial pancreas and type 1 diabetes
M Nwokolo, R Hovorka - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Diabetes technologies represent a paradigm shift in type 1 diabetes care. Continuous
subcutaneous insulin infusion (CSII) pumps and continuous glucose monitors (CGM) …
subcutaneous insulin infusion (CSII) pumps and continuous glucose monitors (CGM) …
Feasibility of closed-loop insulin delivery in type 2 diabetes: a randomized controlled study
OBJECTIVE Closed-loop insulin delivery offers a promising treatment option, but to date, it
has only been evaluated in type 1 diabetes. Our aim was to evaluate the feasibility of fully …
has only been evaluated in type 1 diabetes. Our aim was to evaluate the feasibility of fully …
[HTML][HTML] Day-and-night glycaemic control with closed-loop insulin delivery versus conventional insulin pump therapy in free-living adults with well controlled type 1 …
Background Tight control of blood glucose concentration in people with type 1 diabetes
predisposes to hypoglycaemia. We aimed to investigate whether day-and-night hybrid …
predisposes to hypoglycaemia. We aimed to investigate whether day-and-night hybrid …
Dual‐hormone artificial pancreas for glucose control in type 1 diabetes: A meta‐analysis
B Zeng, H Jia, L Gao, Q Yang, K Yu… - Diabetes, Obesity and …, 2022 - Wiley Online Library
Aim To evaluate the efficacy and safety of a dual‐hormone artificial pancreas (DH) in type 1
diabetes. Material and Methods PubMed, Embase, the Cochrane Library and ClinicalTrials …
diabetes. Material and Methods PubMed, Embase, the Cochrane Library and ClinicalTrials …
Fully closed loop glucose control with a bihormonal artificial pancreas in adults with type 1 diabetes: an outpatient, randomized, crossover trial
H Blauw, AJ Onvlee, M Klaassen, AC Van Bon… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE To demonstrate the performance and safety of a bihormonal (insulin and
glucagon) artificial pancreas (AP) in adults with type 1 diabetes. RESEARCH DESIGN AND …
glucagon) artificial pancreas (AP) in adults with type 1 diabetes. RESEARCH DESIGN AND …